Zimmer Orthobiologics, Inc.

Margarete Akens

Pedro Bittmann

Daniel Nadler

Jörg Auer

Brigitte Rechenberg

Repairs of cartilage defects or of cartilage/bone defects in human or animal joints with the help of devices including a bone part (), a cartilage layer () and a subchondral bone plate () or an imitation of such a plate in the transition region between the cartilage layer () and the bone part (). After implantation, the bone part () is resorbed and is replaced by reparative tissue only after being essentially totally resorbed. In a critical phase of the healing process, a mechanically inferior cyst is located in the place of the implanted bone part (). In order to prevent the cartilage layer () from sinking into the cyst space during this critical phase of the healing process the device has a top part () and a bottom part (), wherein the top part () consists essentially of the cartilage layer () and the subchondral bone plate () and the bottom part () corresponds essentially to the bone part () and wherein the top part () parallel to the subchondral bone plate () has a larger diameter than the bottom part (). After implantation in a suitable opening or bore (), the cartilage layer () and the subchondral bone plate () are supported not only on the bone part () but also on native bone tissue having a loading capacity not changing during the healing process. Therefore, the implanted cartilage layer cannot sink during the healing process.

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Zurich, Switzerland

Margarete Akens