Hunter Immunology Limited

Other

Auspharm International Limited

Flustat Pty. Ltd.

Pneumobiotics Pty. Ltd.

Margaret Lorraine Dunkley

Robert Llewellyn Clancy

Allan William Cripps

Gerald Toh Pang

Jennelle Kyd

Diana Christine Otczyk

Robert Liewellyn Clancy

Gerald Pang

Robert Clancy

Provided are non-typeablevaccines useful for the treatment of chronic obstructive pulmonary disease and asthma in a patient. In certain aspects, the vaccine is a monobacterial vaccine. Bacterial strains for use in the vaccines of the present application are also provided.

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There is provided a method for prophylaxis or treatment of asthma in an individual. The method comprises administering to the individual an effective amount of a Non-typable(NTHi) vaccine. The vaccine is typically an oral whole killed NTHi vaccine.

Treatment or prophylaxis of asthma

The present invention is concerned with novel compositions and vaccines useful for prophylactic an/or therapeutic treatment of mucosal infections, and in particular it is concerned with oral vaccines and with methods of enhancing mucosal resistance to infection or for treating established infections, of the respiratory tract.

Compositions and methods for treatment of mucosal infections

A novel antigen fromis provided. The use of the antigen in detecting/diagnosingas well as its use in eliciting an immune response are also provided.

Red blood cells or derivatives thereof such as ghost preparations, whole cell membrane preparations or fragments thereof, can act as a potent carrier for orally administered antigens. Mucosal immunity in particular can be effectively induced against such viruses as influenza when adsorbed to chicken red blood cells and orally administered.

Growing community of inventors

New South Wales, Australia

Margaret Lorraine Dunkley