Janssen Pharmaceutica Nv

Margaret Fedgchin

Jaskaran Singh

Ella Daly

Wayne C Drevets

Frank Wiegand

Lodewijk Ivo Caers

Peter Nicholas Zannikos

Carla Marie Canuso

Vanina Popova

David Wood Hough

The present invention provides methods for treating depression in a patient, comprising administering to the patient in need of the treatment a therapeutically effective amount of esketamine. In some embodiments, the depression is major depressive disorder or treatment resistant depression. In other embodiments, the therapeutically effective amount is clinically proven safe and/or effective. Also provided are methods to mitigate the risk or misuse or abuse of esketamine, instructions for use of the esketamine product, and methods for selling a drug product containing esketamine.

Esketamine for the treatment of depression

The present invention is directed to methods and dosing regimens for the treatment of depression (preferably, treatment resistant depression), for the treatment of depression in a suicidal patient, and/or for the treatment and/or prevention of suicidality (e.g. suicidal ideations).

Methods for the treatment of depression

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Collegeville, PA, United States of America

Margaret Fedgchin