Harbinger Medical, Inc.

Medtronic, Inc.

Marek Malik

Harold H Hoium

Stephen James Ryan

Burak Acar

Velislav Nikolaev Batchvarov

A system and method for detecting a patient's susceptibility to arrhythmias and cardiac tissue abnormality is disclosed. The method consists of using a computer, a display, software loaded onto the computer that generates graphical user interfaces (GUIs), an electronic interface, and a plurality of electrodes. The electronics interfaceis in electronic communication with the computer, and further in electronic communication with the electrodes that are placed by self-adhesion at predetermined locations on a test subject. According to one aspect of the invention, the method enables a user, typically a medical professional, to initiate, with minimal input, certain diagnostic tests involving observing and analyzing a series of QRS complexes, some of which are biased with a subpacing current, and others of which are unbiased. The signals are then compared, and the differences are analyzed to detect a patient's susceptibility to arrhythmias and cardiac tissue abnormality.

Method of noninvasively determining a patient's susceptibility to arrhythmia

A system and method for detecting a patient's susceptibility to arrhythmias and cardiac tissue abnormality is disclosed. The method consists of using a computer, a display, software loaded onto the computer that generates graphical user interfaces (GUIs), an electronic interface, and a plurality of electrodes. The electronics interface is in electronic communication with the computer, and further in electronic communication with the electrodes that are placed by self-adhesion at predetermined locations on a test subject. According to one aspect of the invention, the method enables a user, typically a medical professional, to initiate, with minimal input, certain diagnostic tests involving observing and analyzing a series of QRS complexes, some of which are biased by passively altering the impedance of the patient's body, and others of which are unbiased. The signals are then compared, and the differences are analyzed to detect a patient's susceptibility to arrhythmias and cardiac tissue abnormality.

A system and method for detecting a patient's susceptibility to arrhythmias and cardiac tissue abnormality is disclosed. The method consists of using a computer , a display , software loaded onto the computer that generates graphical user interfaces (GUIs), an electronic interface , and a plurality of electrodes. The electronics interface is in electronic communication with the computer , and further in electronic communication with the electrodes that are placed by self-adhesion at predetermined locations on a test subject . According to one aspect of the invention, the method enables a user, typically a medical professional, to initiate, with minimal input, certain diagnostic tests involving observing and analyzing a series of QRS complexes , some of which are biased with a subpacing current, and others of which are unbiased. The signals are then compared, and the differences are analyzed to detect a patient's susceptibility to arrhythmias and cardiac tissue abnormality.

A system and method for detecting a patient's susceptibility to arrhythmias and cardiac tissue abnormality is disclosed. The method consists of using a computer, a display, software loaded onto the computer that generates graphical user interfaces (GUIs), an electronic interface, and a plurality of electrodes. The electronics interface is in electronic communication with the computer, and further in electronic communication with the electrodes that are placed by self-adhesion at predetermined locations on a test subject. According to one aspect of the invention, the method enables a user, typically a medical professional, to initiate, with minimal input, certain diagnostic tests involving observing and analyzing a series of QRS complexes, some of which are biased with a subpacing current, and others of which are unbiased. The signals are then compared, and the differences are analyzed to detect a patient's susceptibility to arrhythmias and cardiac tissue abnormality.

New methods of characterising ventricular operations by measuring propagation characterisics of the repolarisation wavefront (the T wave) are disclosed, the methods use new descriptions of T wave Morphology Dispersion (TMD), Total Cosin R_ to _T (TCRT) and T wave energy residium to quantify the wavefront characteristics, these descriptors measure the spatial variability of the T wave Morphology, the vector deviations between the depolarisation and repolarisation wavefronts and the energy of the non-dipolar components of the ECG vector respectively. TCRT also provides a responsive descriptor for measuring autonomic tone. As such, has applications for improved pacing and autonomic nervous system monitors.

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London, United Kingdom

Marek Malik