Instrumentarium Corporation

Ge Healthcare Finland Oy

Marcus Johannis Van Gils

Matti Veli Tapani Huiku

Ilkka Korhonen

Markku Paloheimo

Arvi Yli-Hankala

Mikko Oskari Jousi

Jyrki Mika Petteri Lötjönen

The invention relates to a method for monitoring a condition of a patient under anesthesia or sedation, whereupon one, two, three or more signals are acquired, and the signal(s) represent(s) cardiovascular and/or combined electrical biopotential on skull activity of the patient. From said signal or signals are derived or calculated at least two parameter values related to a quantity like waveform amplitude, waveform periodicity, waveform morphology, waveform variability, energy, power, signal complexity and frequency content. A predetermined mathematical index for probability of patient comfort is used, in which function said parameters are variables, and successively changing probability index values of said mathematical index is calculated.

Method and apparatus based on combination of physiological parameters for assessment of analgesia during anesthesia or sedation

The invention concerns a method and an apparatus for monitoring a condition of a patient under anesthesia or sedation. For this purpose there is a sensor for acquiring a signal that represents peripheral cardiovascular flow in the patient. Successive heart beat pulses are detected and predetermined pulse wave parameters are measured repeatedly in said signal, and predefined pulse wave parameters within said heart beat pulses are measured, too. At first, said predetermined pulse wave parameters in a number of successive heart beat pulses are compared in respect to possible occurrence of a substantial alteration. At second, if the alteration is noticed, a statistical reference value is calculated by deriving values from at least said predefined pulse wave parameters, and the change(s) between at least one predefined pulse wave parameter and said reference value is quantified. The results and/or intermediate results are finally displayed and/or recorded.

Method and an apparatus for pulse plethysmograph based detection of nociception during anesthesia or sedation

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Tampere, Finland

Marcus Johannis Van Gils