Ideaya Biosciences, Inc.

Marcos Gonzalez-Lopez

Hilary Plake Beck

James Clifford Sutton, Jr

Muzaffar Alam

Leah Cleary

Alice Chen Rico

Luis Ruben P Martinez

James Clifford Sutton

Provided herein are compounds, compositions and methods of using the compounds and compositions for the treatment of diseases modulated, as least in part, by AhR. The compounds are represented by formulae: wherein the letters and symbols X, X, Z, R, R, R, R, R, R, Rand Rhave the meanings provided in the specification.

AhR modulators

Compounds are provided having Formula (I): wherein R, R, Cyc and A have the meanings provided herein. The compounds have utility in the treatment of diseases, either alone or in combination with other agents.

Dihydrothieno[3,2-b]pyridine compounds

Provided herein are compounds, compositions and methods of using the compounds and compositions for the treatment of diseases modulated, as least in part, by AhR. The compounds are represented by formulae Formula (I), (II), (III), (iv): wherein the letters and symbols a, b, c, d, e, f, g, Z, R, Rand Rhave the meanings provided in the specification. 

Amido compounds as AhR modulators

Provided herein are compounds, compositions and methods of using the compounds and compositions for the treatment of diseases modulated, as least in part, by AhR. The compounds are represented by formula: wherein the letters and symbols a, b, c, d, e, f, A, R, X, Arand Arhave the meanings provided in the specification.

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South San Francisco, CA, United States of America

Marcos Gonzalez-Lopez