Bayer Cropscience Ag

Bayer Intellectual Property Gmbh

Bayer Animal Health Gmbh

Marco Brünjes

Mark James Ford

Isolde Häuser-Hahn

Hansjörg Dietrich

Christopher Hugh Rosinger

Elmar Gatzweiler

Michael Gerhard Hoffmann

Ulrike Wachendorff-Neumann

Dieter Feucht

Stefan Lehr

Jean-Pierre A Vors

Philippe Rinolfi

Jan Dittgen

Christophe Dubost

Ines Heinemann

Hartmut Ahrens

Dirk Schmutzler

Stephane Brunet

Uwe Döller

Cyril Montagne

Philipp Winter

Harmut Ahrens

The present invention generally relates to improved processes for the preparation of amphiphilic imidazolinium compounds such as 1-[2-(9(Z)-octadecenoyloxy)ethyl]-2-(8(Z)-heptadecenyl)-3-(2-hydroxyethyl)imidazolinium chloride (DOTIM). In particular, the invention relates to processes for the synthesis of such compounds that avoid the need for toxic reagents, are more economical, and result in less waste than conventional methods. DOTIM and similar compounds can be formulated as cationic liposomes, which are useful as chemical vectors for nucleic acid delivery in gene therapy.

Process for the preparation of amphiphilic imidazolinium compounds

The present invention relates to novel difluoromethyl-nicotinic indanyl carboxamides, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials.

Difluoromethyl-nicotinic-indanyl carboxamides

The present invention describes a novel process for preparing piperidine-4-carbothioamide.

Preparation of piperidine-4-carbothioamide

The present invention relates to novel herbicidally active 6-(2-aminophenyl)picoline derivatives and to processes for preparation thereof. The present invention further provides for the use thereof as a herbicide, especially as a herbicide for selective control of weed plants in useful plant crops, and as a plant growth regulator alone or in combination with safeners and/or in a mixture with other herbicides.

6-(2-aminophenyl)picolinates and their use as herbicides

The present invention relates to novel, herbicidally active picolinic acid derivatives of the formula (I) and to processes for preparation thereof. The present invention further provides for the use thereof as a herbicide, especially as a herbicide for selective control of weed plants in useful plant crops, and as a plant growth regulator alone or in combination with safeners and/or in a mixture with other herbicides.

Substituted picolinic acids, salts and acid derivatives thereof, and use thereof as herbicides

The invention relates to compounds of the formula (I) and N-oxides, tautomers and agrochemically compatible salts thereof to processes for their preparation, and to their use as herbicides and plant growth regulators, in particular as herbicides for the selected control of harmful plants in useful plant crops.

Pyrimidin-4-ylpropanedinitrile derivatives, processes for their preparation and their use as herbicides and plant growth regulators

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Hattersheim am Main, Germany

Marco Brünjes