Rhone-poulenc Chimie

Rhodia Chimie

Rhone-poulenc Agrochimie

Centre National De La Recherche Scientifique

Rhone-poulenc Specialites Chimiques

Electricite De France - Service National

Rhone-poulenc Specialties Chimiques

Marc Tordeux

Claude Wakselman

Bernard Langlois

Catherine Francese

Nicolas Roques

Jean-Louis Clavel

Roland Nantermet

Laurent Saint-Jalmes

Gerard Forat

G&eacute;rard Forat

Laurent Petit

Amaya Berecibar

Hatem Marzouk

A reagent comprising a compound of formula (I): R &mdash;M(X)(Z) &mdash;Y&mdash;R, wherein R is a hydrocarbon radical advantageously having at most 10 carbon atoms and being selected from alkyls and aryls; R is a radical of formula II: R &mdash;(C&Xgr; ) &mdash;CF &mdash;, where R is a fluorine or chlorine atom or a carbon radical, m is 0 or a integer from 0-12, and each &Xgr;, which may be the same or different, is a chlorine or preferably fluorine atom, with the proviso that when m is 0, R is electroattractive, preferably a fluorine atom; n is 0 or 1; M is a non-metal selected from carbon and chalcogens with an atomic number than oxygen; and each of X, Y and Z, which are the same or different, is a chalcogen; as well as a generator, for consecutive or simultaneous addition. The reagent is useful for organic synthesis.

Reactant, compound and process for the perfluoroalkylation of a nucleophile, and the derivatives obtained

The invention concerns a method for the condensation of aromatic derivative(s) or a sulphinic derivative by a perhalogenated, advantageously perfluorinated, carbon atom. Said method is characterized in that it consists in subjecting said sulphinic derivative and said aromatic derivative to the action of a strong acid whereof the pKa is not more that 0. The invention is applicable to organic synthesis.

Method for condensation of aromatic derivative(s) and a sulphinic derivative

Reactant, compound and process for the perfluoroalkylation of the

Method for preparation of perfluoroalcanecarboxylic and

The present invention relates to a process for the preparation of perhaloalkylthioethers by bringing a perhaloalkyl halide, preferably a bromide or an iodide, into contact with a disulphide in the presence of zinc and of sulphur dioxide or of a dithionite or of a hydroxymethanesulphinate or of a formate anion and sulphur dioxide.

Process for the preparation of perhaloalkylthioethers

A process for the preparation of perhaloalkanesulfinic and -sulfonic acids and derivatives of these acids. A perhaloalkanesulfinic acid salt is prepared by contacting a metal hydroxymethanesulfinate (preferably, a sodium, zinc or copper hydroxymethanesulfinate) with a perhaloalkyl halide group, in a polar solvent. Optionally, the perhaloalkanesulfinic acid salt is then converted to a perhaloalkanesulfinic or -sulfonic acid or a derivative of either of these acids.

Process for the preparation of perhaloalkanesulfinic and -sulfonic

A process for the preparation of perfluoroalkylated ketones and/or perfluoroalkylated alcohols, comprising the step of contacting a perfluoroalkyl iodide or perfluoroalkyl bromide with an acid anhydride, in the presence of a metal chosen from zinc and cadmium.

Process for perfluoroalkylation of acid anhydrides

A process for the preparation of a perfluoroalkyl ketone. A perfluoroalkyl halide, zinc and an ester are brought into contact with one another. Preferably a polar aprotic solvent and/or a pyridine is also present.

Process for the preparation of perfluoroalkyl ketones

A process for the preparation of trifluoromethyl iodide by bringing into contact with one another to form a reaction product either:

Process for the preparation of trifluoromethyl iodide

A process for the preparation of a benzyl trifluoromethyl sulfide by bringing a benzyl thiocyanate and trifluoromethyl bromide into contact with zinc in a polar aprotic solvent or a pyridine. The invention also relates to a process for the preparation of trifluoromethane sulfonyl chloride by bringing a benzyl trifluoromethyl sulfide into contact with chlorine and water.

Process for the preparation of benzyl trifluoromethyl sulfide

A process for the perfluoroalkylation of aromatic derivatives. In a first stage, an aromatic derivative, sulfur dioxide and a metal selected from the group consisting of zinc, aluminum, manganese, cadmium, magnesium, tin, iron, nickel and cobalt, are brought into contact in a solvent, preferably a polar aprotic solvent. In a second stage, a perfluoroalkyl bromide or iodide is added to react with the aromatic derivative.

Process for perfluoroalkylation of aromatic derivatives

A process for the preparation of perfluoroalkylated alcohols and esters by bringing a carbonyl-containing derivative and a perfluoroalkyl iodide or bromide into contact with zinc, preferably in the presence of a polar aprotic solvent and/or a pyridine.

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Sceaux, France

Marc Tordeux