Other

Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V.

Imd Natural Solutions Gmbh

Imd Natural Solutions Gmb

Universität Des Saarlandes

Grothe, Torsten

Stadler, Marc

Marc Stadler

Stefan Jennewein

Rolf Müller

Jens Bitzer

Bärbel Köpcke

Kathrin Reinhardt

Torsten Grothe

Jana Moldenhauer

Thomas Küper

Ernst Roemer

Ronald O Garcia

Benedikt Engels

Dominik Pistorius

Philipp Wabnitz

Barbel Kopcke

The invention relates to the use of, and methods of use employing, certain glycolipid compounds as defined in detail below and having preservative or antimicrobial properties, novel compounds of the glycolipid class, and related invention embodiments. The compounds have the formula I wherein m is 3 to 5, n is 2 to 5, o is 0 or 1 and p is 3 to 17, with the proviso that the sum m+n+o+p is not less than 14; andR is a carbohydrate moiety bound via one of its carbon atoms to the binding oxygen,and/or a physiologically, especially pharmaceutically or nutraceutically or cosmetically, acceptable salt thereof, or an ester thereof,as such or in the form of a composition,where the compound may be present in open chain form and/or in the form of a lactone (FIG.).

Long chain glycolipids useful to avoid perishing or microbial contamination of materials

The invention relates to compositions and methods (with regard to animals and humans) for utilizing an extract and/or one or more natural spiro triterpenoids and derivatives thereof alone or as a supplement. Certain materials utilized are from the blazeispirol family, obtainable fromspecies. Treatments include the prophylactic and/or therapeutic treatment of a disease, disorder or condition that responds to the modulation of Liver X receptor, as well as corresponding methods of treatment, the manufacture of a pharmaceutical and nutraceutical formulation for said treatment. The invention also relates to the use of the extract and compound(s) in the treatment or in the preparation of a medicament (e.g. a nutraceutical) for the prophylactic and/or therapeutic treatments, as well as their preparation. It also relates to pharmaceutical or nutraceutical formulations described herein which are useful in prophylactic and therapeutic treatments. They can also be used for non-therapeutic, e.g. cosmetic, purposes.

Terpenoid spiro ketal compounds with LXR agonists activity, their use and formulations with them

The present invention relates to an isolated, recombinant or synthetic polynucleotide encoding a polypeptide with protoilludene synthase activity and comprising a sequence selected from the group consisting of a) SEQ ID Nos. 1 or 14 of the attached sequence listing; b) a nucleic acid sequence complementary to SEQ ID Nos. 1 or 14; c) nucleic acid sequences which hybridize under stringent conditions to the nucleic acid sequences defined in a) and b) or their complementary strands, as well as to the polypeptide encoded by the isolated polynucleotide, as well as a method for the production of melleolides employing the polynucleotide or polypeptide of the invention.

Protoilludene synthase

Growing community of inventors

Niederkirchen, Germany

Marc Stadler