Atritech, Inc.

Intuitive Surgical Operations, Inc.

Proteus Digital Health, Inc.

Abbott Cardiovascular Systems, Inc.

Ev3 Sunnyvale, Inc.

Covidien LP

Ev3 Endovascular, Inc.

Snap-on Technologies, Inc.

Datascope Corporation

Resonex Holding Company

Terus Medical, Inc.

Artritech, Inc.

Technology Funding Secured Investors Ii

Otsuka Pharmaceutical Company, Limited

Marc S Kreidler

Andrew G C Frazier

Alexander K Khairkhahan

Erik Van Der Burg

Chad C Roue

Alan Klenk

Stewart M Kume

Darrell H Ogi

Michael D Lesh

Robert Matthew Ohline

Charles E Swinehart

Aaron W Brown

Katherine Whitin

Scott J Reiner

Amir Belson

Christopher Allen Julian

Mark Harasym

Enrique Romo

Mark Zdeblick

Andrew S Thompson

Timothy Robertson

Hooman Hafezi

George M Savage

Lawrence W Arne

Yashar Behzadi

Robert Duck

Robert C Leichner

Dino De Cicco

James Hutchison

Fataneh Omidvar

Jessica P Miller

Kenneth Rowberry

Andrew Thompson

Robert Leichner

Chris A Julian

David T Hung

Harrie J Wolters

Dino DeCicco

Rodney E Bell

Keith Phillip Laby

Andrew Frazier

Bruce Robert Woodley

Wade A Keller

Joshua T Oen

Marc Jensen

Ashik A Mohan

Lawrence Kerver

Joseph N Lamberti

James Craig Milroy

Willy Borner

Jacques Van Dam

Chuckson M Yokota

Erik J Van Der Burg

Eric Knisley

David Huynh

Juan Perez

Robert L Moya

Erin A Ryan

Charles P Ho

Alan R Klenk

Alex K Khairkhahan

Aaron Wesley Brown

Scott James Reiner

A medical instrument may comprise a first articulatable segment having a first diameter, and a second articulatable segment having a second diameter smaller than the first diameter, wherein the second articulatable segment is coupled to the first articulatable segment and extends in a distal direction past the first articulatable segment. The instrument may also comprise a first force transmission element coupled to the first articulatable segment and extending in a proximal direction from the first articulatable segment to a first connector portion, the first connector portion being configured to be releasably coupled with a first actuator, and a second force transmission element coupled to the second articulatable segment and extending in a proximal direction from the second articulatable segment to a second connector portion, the second connector portion being configured to be releasably coupled with a second actuator. The first and second force transmission elements may be configured to transmit actuation forces, respectively, to articulate the first and second articulatable segments independently of one another.

Connector device for a controllable instrument

A surgical applicator for a fastener, the surgical applicator comprising: a handle; a trigger movable relative to the handle between an initial position, an actuated position, and an intermediate position between the initial position and the actuated position; and a lockout mechanism movable relative to the trigger between a locked position and an unlocked position, the lockout mechanism operatively arranged to: lock the trigger in the intermediate position when the trigger is moved from the initial position toward the actuated position; and permit movement of the trigger from the intermediate position toward the initial position or the actuated position when the lockout mechanism is moved from the locked position to the unlocked position.

Device for atrial appendage exclusion

A method of preventing ingress of material into the left atrium of a heart includes providing a delivery sheath, advancing the sheath distal end through an opening between the right atrium and the left atrium of the heart, providing an expandable cage, delivering the expandable cage to the left atrium, and expanding the expandable cage within the left atrium. The expandable cage includes a proximal end, a distal end, and a plurality of supports extending therebetween. The expandable cage also includes a first membrane provided at its proximal end and a second membrane provided at its distal end. The expandable cage has a collapsed configuration so that it can be received within the lumen of the delivery sheath, and an expanded configuration for deployment within the heart. When expanded, the first membrane is positioned at an opening between the left and right atria of the heart, and the second membrane is positioned at the ostium of the left atrial appendage. The first membrane substantially prevents passage of blood between the atria and the second membrane prevents passage of embolic material from the left atrial appendage into the left atrium of the heart.

Intracardiac cage and method of delivering same

A connector assembly for controllable articles is described herein. The connector assembly engages force transmission elements used to transmit force from one or more force generators with the force transmission elements used to manipulate a controllable article. Additionally, the connector assembly provides organization thereby simplifying the process of connecting a plurality of elements, usually with a quick, single movement.

Disclosed is an adjustable occlusion device for use in a body lumen such as the left atrial appendage. The occlusion device is removably carried by a deployment catheter. The device may be enlarged or reduced to facilitate optimal placement or removal. Methods are also disclosed.

Method of implanting an adjustable occlusion device

The application discloses devices, delivery tools, systems, and methods for treating biliary disease. Device comprise, for example, a component configured for deployment between a gallbladder and location within a gastrointestinal tract of a patient which has a proximal end and a distal end with a lumen extending therethrough. A method of deploying the device can be achieved by, for example, creating a duct or fistula between a gallbladder lumen and a portion of a gastrointestinal tract; and providing for drainage from the gallbladder to the gastrointestinal tract.

Biliary shunts, delivery systems, and methods of using the same

A stent design reduces the likelihood of contact among structural members when the stent diameter is reduced before insertion into the body. In one approach, an undulating link has a J-shaped profile or has an angled portion on one side at the peak of the link, in order to reduce contact during crimping. The stent may also include structural features that improve such aspects as flexibility, the coatibility of a drug coating onto the stent, flare reduction, stent retention within the body and/or reduction of the minimum diameter of the stent during crimping.

Intravascular stent

A stent design reduces the likelihood of contact among structural members when the stent diameter is reduced before insertion into the body. In one approach, an undulating link has a J-shaped profile or has an angled portion on one side at the peak of the link, in order to reduce contact during crimping. The stent may also include structural features that improve such aspects as flexibility, the coatability of a drug coating onto the stent, flare reduction, stent retention within the body and/or reduction of the minimum diameter of the stent during crimping.

A device for containing emboli within a left atrial appendage of a patient includes a frame that is expandable from a reduced cross section to an enlarged cross section and a slider assembly. There is provided in accordance with various embodiments of the present invention methods of preventing retention anchors from projecting outside of the native diameter of the frame, thus facilitating recapture of the device.

System and method for delivering a left atrial appendage containment device

The present invention relates, generally, to the reduction or elimination of permanent and catastrophic herniations in Bowden cables or coil pipes in articulating devices or snake-like robots. More particularly, the present invention relates managing the coil pipes in a spiral pattern along the articulating device or snake-like robot to reduce or eliminate the necessity of the Bowden cables or coil pipes to slide along the length of the articulating device or snake-like robot. Reduction or elimination of the necessity for the Bowden cables or coil pipes to slide reduces or eliminates catastrophic herniations in articulating devices or snake-like robots undergoing one or more articulations.

System for managing Bowden cables in articulating instruments

Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.

Body-associated receiver and method

Disclosed is an apparatus for facilitating access to the left atrium, and specifically the left atrial appendage. The apparatus may comprise a sheath with first and second curved sections that facilitate location of the fossa ovalis and left atrial appendage. The apparatus may further comprise tissue piercing and dilating structures. Methods are also disclosed.

Method and apparatus for accessing the left atrial appendage

Growing community of inventors

Sunnyvale, CA, United States of America

Marc S Kreidler