Cordis Corporation

Cordis Neurovascular, Inc.

University of Pittsburgh

Regentys Corporation

Marc Ramer

Frank Butaric

Kenneth S Solovay

William L Howat

Zevulen Fayngold

Durmus Koch

Donald K Jones

Stephen Francis Badylak

Luis A Davila

Robert P Letendre

George Landau

Dieter Stoeckel

Gregory S Mast

Bill K Ng

Andrew Yanez

Timothy Keane

Methods and compositions for treating diseased or damaged tissue, such as Inflammatory Bowel Disease, e.g., Ulcerative Colitis, include tissue regeneration using stem cells or tissue grafts which stimulate stem cell migration to the damaged tissue. The tissue grafts can be extracellular matrix (ECM) material, such as tissue-specific extracellular matrix (TS-ECM). The methods can also include mucosal resection of the damaged or diseased tissue prior to placement of the graft.

Method and composition for treating inflammatory bowel disease

In accordance with the present invention there is provided a stent graft for insertion into a body vessel of a patient, the stent graft includes a hollow substantially cylindrical radially expandable stent having a body, two open ends and a longitudinal axis therebetween. The body of the stent is made from a plurality of interconnected struts. The stent graft further includes a graft member attached to the body of the stent, wherein the graft member having a plurality of substantially longitudinally directed pleats disposed thereon. In a particularly preferred embodiment, the graft further includes a plurality of radially oriented pleat interruptions disposed thereon.

Stent graft having a pleated graft member

A stent-graft for insertion into a body lumen, such as a blood vessel, is utilized in order to repair such lumen. The stent-graft includes a substantially cylindrical hollow expandable stent comprising a plurality of interconnected struts. The stent has a distal end and a proximal end, and an interior surface and an exterior surface. At least one strut of the stent has first and second apertures extending therethrough from the interior surface to the exterior surface. The stent-graft also includes a graft member covering a predetermined portion of least one of the interior surface and the exterior surface of the stent. In addition, the stent-graft further includes a staple for attaching the graft member to the stent. The staple has a crown and two legs extending therefrom. At least one of the legs of the staple extends through the graft material and through the first aperture. Both of the legs are bent inwardly towards said crown such that they evert back and extend through the second aperture.

Stent for use in a stent graft

The present invention is directed to a system, apparatus, and method for treating, repairing, and/or replacing an aneurysm, preferably an aortic aneurysm, and most preferably, an abdominal aortic aneurysm. The systems, devices, and methods of the present invention include a first prosthesis or stent gasket, and at least one second prosthesis for bypassing the aneurysm. In preferred embodiments, the second prosthesis includes a branch leg that may be disposed and anchored in an either a cross artery or a downstream artery to facilitate fluid flow. In other preferred embodiments, at least one third prosthesis is provided for establishing a fluid flow channel through a second diseased artery to bypass an aneurysm disposed therein. In accordance with the invention, the first artery may be the abdominal aorta and the second artery may be an iliac artery.

Stent graft with branch leg

The invention is a system, apparatus, and method for treating, and/or repairing an aneurysm, preferably an aortic aneurysm, and most preferably, an abdominal aortic aneurysm. The systems, devices, and methods of the present invention include a prosthesis assembly for establishing a fluid flow path between an upstream portion of an artery and at least one bifurcated downstream portion of the artery.

Bilateral extension prosthesis and method of delivery

An aneurysm neck covering device which is particularly useful for sealing the neck of an aneurysm located in the vicinity of a bifurcated blood vessel. The neck covering device includes a self-expanding stent for supporting and retaining a self-expanding neck cover which seals the neck of the aneurysm.

Neck covering device for an aneurysm

An expandable stent having a covering which exhibits the characteristic of being normally dissolvable in blood, but upon being activated, becomes inert to blood. The stent may be placed across the neck of an aneurysm to seal the aneurysm and thereafter the portion of the covering of the stent across the neck of the aneurysm is activated to become inert to blood and the balance of the covering dissolves to permit blood to flow to adjacent vessels.

Expandable stent having a stabilized portion

An endoluminal aneurysm treatment system of an expandable bypass prosthesis and an extension prosthesis with a flared distal portion which, upon expansion, frictionally engages the proximal end of the bypass prosthesis.

Extension prosthesis for an arterial repair

Stent graft having an improved means for attaching a stent to a graft

A stent-graft for insertion into a body vessel of a patient includes a hollow substantially cylindrical radially expandable stent having a body, two open ends and a longitudinal axis therebetween. The body of the stent is made from a plurality of interconnected struts. The stent-graft further includes a graft member attached to the body of the stent, wherein the graft member has a plurality of substantially longitudinally directed pleats disposed thereon. The graft further includes a plurality of radially oriented pleat interruptions disposed thereon.

Growing community of inventors

Weston, FL, United States of America

Marc Ramer