Cis Bio International

Marc Preaudat

Eric Trinquet

G&eacute;rard Mathis

Chikashi Tokuda

Laurence Jacquemart

The invention relates to a method for determining endoglycosidase enzyme activity, and in particular of the heparanase type, in a sample, and also to a method for detecting a compound capable of modulating the activity of an endoglycosidase, and in particular of an endoglycosidase having activity of the heparanase type, by measuring a signal resulting from a close proximity transfer between two compounds attached to a substrate for the enzyme.

Method for determining endoglycosidase enzyme activity

The invention relates to a novel homogeneous method of detecting and/or determining the phosphorylating activity of a biological material towards a substrate containing tyrosine and/or serine and/or threonine, and to a kit for carrying out this method.

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Connaux, France

Marc Preaudat