Pierre Fabre Medicament

Marc Marien

Bernard Vacher

Bernard Bonnaud

Peter Pauwels

Thierry Imbert

Francis Colpaert

Patrice Mayer

Jean-Claude Martel

Peters Pauwels

The invention provides methods of treating a memory deficiency in a subject in need of such treatment, where the methods comprise administering to a subject an effective amount of a compound of formula (1): wherein: R1 is hydrogen, fluorine or a methoxyl group, R1 being in position 2, 3, 4 or 5 of the aromatic carbocycle; R2 is hydrogen or a methyl group; R3 is hydrogen, a methyl group or an ethyl group; and their pharmaceutically acceptable acid addition salt as well as the isomers and the tautomers thereof. The memory deficiency may be correlated with a memory deficiency induced by scopolamine.

Imidazolic compounds and use thereof as alpha-2 adrenergic receptors

The invention provides methods of treating a memory deficiency in a subject in need of such treatment, where the methods comprise administering to a subject an effective amount of a compound of formula (1): 

The invention provides compounds having the formula (1): wherein R1 is hydrogen, fluoro or methoxyl, R1 being in position 2, 3, 4 or 5 of the aromatic carbocycle; R2 is hydrogen or methyl; R3 is hydrogen, methyl or ethyl; and their pharmaceutically acceptable acid addition salts, hydrates of their pharmaceutically acceptable acid addition salts as well as the isomers and the tautomers thereof.

Imidazolic compounds and use thereof as alpha-2-adrenergic receptors

Fluorinated imidazoline benzodioxane, preparation and therapeutic uses thereof

Use of efaroxan for producing medicine for treating huntington 's disease

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Castres, France

Marc Marien