Danisco US Inc.

Genencor International, Inc.

Danisco A/s

Genecor International, Inc.

Danisco US Inc., Genencor Division

Danison US Inc.

Marc Kolkman

Brian E Jones

Chris Leeflang

David Aaron Estell

Lilia Maria Babe

Casper Vroemen

Melodie Estabrook

Andrew Shaw

Walter Weyler

Rie Mejldal

Ayrookaran J Poulose

Scott Douglas Power

Hiroshi Oh

Anita Van Kimmenade

Richard Ray Bott

Frits Goedegebuur

Clement K Choy

Katherine D Collier

Karsten Matthias Kragh

Wolfgang Aehle

Luis Gustavo Cascao-Pereira

Brian Frederick Schmidt

Harm Jan Mulder

Gudrun Vogtentanz

Jeffrey V Miller

Ronaldus W J Hommes

Grant C Ganshaw

George R England

Hans De Nobel

Claudine Chang

Wilhelmus A H Van Der Kley

Leonardus P M Van Marrewijk

Anja Hemmingsen Kellett-Smith

James T Kellis, Jr

Sina Pricelius

Zheyong Yu

Neelam S Amin

Zhen Qian

Miles Christopher Scotcher

Brian Sogaard Laursen

Brian Miller

Eugene Steven Sadlowski

Jian Yao

Anthony G Day

Thomas P Graycar

Slavko Kralj

Jørn Dalgaard Mikkelsen

Sandra W Ramer

Christopher James Murray

Cristina Bongiorni

Xiaogang Gu

Wilhelmus A H Van Der Kleij

Edward M Concar

Roopa Santosh Ghirnikar

Brian S Miller

Anja Hemmingsen Kellett-smith

Christian D Adams

Mansi Goyal

Victoria E Huang

Virgil Arthur Rhodius

Johannes G De Nobel

Veli Alkan

Arjen Hoekstra

Raj Lad

Leo P M Van Marrewijk

Leo Van Marrewijk

Rikke Høegh Lorentsen

Anja Hemmingsen Kellett Smith

The present disclosure relates to serine proteases and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.

Serine proteases

strain WDG185 expresses an inulosucrase that efficiently synthesizes a broad range of IOS with a GF range of GF3-GF30. The isolated and/or purified inulosucrase, recombinantly engineered variants thereof, active fragments thereof, synthetic nucleic acids encoding the inulosucrase, its variants, or its active fragments, host cells comprising the synthetic nucleic acids, and compositions comprising the inulosucrase are provided. Methods of using the compositions include the manufacture of inulooligosaccharides.

Compositions and methods comprising the use of ainulosucrase (INUO)

The instant disclosure is generally related to novel engineered (hybrid) promoters. In certain embodiments, the instant disclosure is directed to one or more nucleic acid compositions comprising engineered promoters operably linked to nucleic acids encoding proteins of interest. Thus, the disclosure set forth herein described methods and compositions for the production of proteins of interest using one or more novel engineered (hybrid) promoters of the disclosure.

Engineered ribosomal promoters for protein production in microorganisms

The present disclosure relates to serine proteases cloned from, and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.

Serine proteases of the-clade

The present disclosure relates to serine proteases cloned fromand, and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.

Methods of makingserine proteases

Aspects of the present compositions and methods relate to novel metalloproteases, polynucleotides encoding the novel metalloproteases, and compositions and methods for use thereof.

Metalloproteases

Serine proteases of the bacillus gibsonii-clade

Disclosed are compositions and methods relating to variant maltohexaose-forming alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing.

Variant maltohexaose-forming alpha-amylase variants

The present invention provides peptides and supported peptides for treating various diseases and conditions. In particularly preferred embodiments, the present invention provides compositions and methods for personal care. In some embodiments the present invention provides compositions for use in skin and/or hair care, as well as cosmetic compositions. IN alternative particularly preferred embodiments, the present invention provides peptides and supported peptides for treating diseases of the skin, such as rosacea. In some particularly preferred embodiments, the supported peptides of the present invention are anti-VEGF peptides. In alternative particularly preferred embodiments, the anti-VEGF peptides are expressed on a scaffold protein. In some most preferred embodiments, the scaffold protein comprises BBI.

Peptide personal care compositions and methods for their use

The present compositions and methods relate to an endo-&#x3b2;-mannanase cloned from, polynucleotides encoding the endo-&#x3b2;-mannanase, and methods of use thereof. Formulations containing the endo-&#x3b2;-mannanase are highly suitable for use as detergents.

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Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.

TS-23 alpha-amylase variants with altered properties

Compositions and methods relating to an alpha-amylase enzyme obtained fromWDG195 are described.

The present invention provides novel Micrococcineae spp serine proteases having multiple substitutions. In particular, the present invention provides serine proteases having multiple substitutions, DNA encoding these proteases, vectors comprising the DNA encoding the proteases, host cells transformed with the vector DNA, and enzymes produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising these serine protease variants. In particularly preferred embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These variant proteases also find use in numerous applications.

Multiple mutation variants of serine protease

Described are compositions and methods relating to variant alpha-amylases having altered biochemical properties and advantageous performance characteristics as compared to a reference alpha-amylase. The variants are suitable for use in various industrial applications such as starch conversion, ethanol production, laundry, dishwashing, pulp and paper production, textile desizing, and/or sweetener production.

Compositions and methods comprising alpha-amylase variants with altered properties

Growing community of inventors

Oegstgeest, Netherlands

Marc Kolkman