Life Technologies Corporation

Alexza Pharmaceuticals, Inc.

Cell Biosciences, Inc.

Proteinsimple

Marc Glazer

Alexander J Mastroianni

Jeremy Gray

Wolfgang Hinz

James A Ball

Phil Waggoner

Christina E Inman

Ronald L Cicero

Yufang Wang

David Cox

Scott Parker

Kimberly Gorrell

Michael L Minto

Tom Weisan Yang

Roger A O'Neill

Martin J Wensley

Dmitriy Gremyachinskiy

Daniel J Myers

Prasanna Krishnan Thwar

David Light

Paul M Kenney

Roman Rozhkov

Ryan Timmons

James Bresson

Joseph Koscinski

Karl O Voss

Daniel J Suich

Mohammad Alanjary

Philip Waggoner

Paul Kenney

Wofgang Hinz

Roger A O`Neill

A sensor component includes a sensor including a sensor surface and a reaction site in cooperation with the sensor and exposing the sensor surface. The reaction site including a reaction site surface. A surface agent is bound to the reaction site surface or the sensor surface. The surface agent includes a surface active functional group reactive with Bronsted base or Lewis acid functionality on the reaction site surface or the sensor surface and including distal functionality that does not have a donor electron pair.

Surface treatment of semiconductor sensors

Drug supply units are disclosed which comprise substrates having a plurality of holes formed therein.

Heating unit for use in a drug delivery device

A sensor apparatus includes a substrate, a semiconductor device disposed over the substrate, the semiconductor device having a surface electrode structure, and a saccharide coating formed over the surface electrode structure. The saccharide coating can be removed prior to use. The semiconductor device can further include a well and optionally a bead disposed in the well.

Surface stabilization of biosensors

A method of forming a polymer matrix array includes treating a surface within a well of a well array with a surface compound including a surface reactive functional group and a radical-forming distal group; applying an aqueous solution including polymer precursors to the well of the well array; and activating the radical-forming distal group of the surface coupling compound with an initiator and atom transfer radical polymerization (ATRP) catalyst to initiate radical polymerization of the polymer precursors within the well of the well array to form the polymer matrix array.

Matrix arrays and methods for making same

A method of forming a polymer matrix array includes applying an aqueous solution into wells of a well array. The aqueous solution includes polymer precursors. The method further includes applying an immiscible fluid over the well array to isolate the aqueous solution within the wells of the well array and polymerizing the polymer precursors isolated in the wells of the well array to form the polymer matrix array. An apparatus includes a sensor array, a well array corresponding to the sensor array, and an array of polymer matrices disposed in the well array.

Methods and apparatus are provided to resolve analytes within a fluid path using isoelectric focusing, gel electrophoresis, or other separation means. Materials within the fluid path that are compatible with these separation means are used to attach resolved analytes to the wall of the fluid path. Attachment results from a triggerable event such as photoactivation, thermal activation, or chemical activation. In accordance with a further aspect of the present invention, the material in the capillary may also be disrupted, by either the triggerable event or a subsequent event such as melting or photocleavage. Thus, an open lumen or porous structure may be created within the fluid path, allowing unbound analyte materials to be washed from the fluid path, and detection agents to be washed into the fluid path. The separation-compatible materials may be polymerizable monomers, gels, entangled polymers or other materials.

Methods and devices for analyte detection

Growing community of inventors

Sunnyvale, CA, United States of America

Marc Glazer