W. R. Grace Co.-conn.

Circe Biomedical, Inc.

Marc E Parham

Joseph T Lundquist

Anthony J Laccetti

RIchard C Hartwig

Victor S Chang

Richard L Duffy

Alan Jay Kishbaugh

Donald T Nicholson

Lawrence F Hancock

James K Kung

James A Avtges

Christian B Lundsager

Richard T Giovannoni

Julie L Rudolph

Lawrence Francis Hancock

A poly(ethyleneoxy) block copolymer including a hydrophobic block segment useful in making a porous polymer article with improved surface hydrophilicity. Also disclosed is a method of making such a polymer article.

Block copolymers

An amphiphilic block copolymer including a hydrophilic internal segment and polymeric articles made therefrom.

Thermoplastic block copolymers

The present invention relates to the efficient removal of low density lipoprotein cholesterol complex (LDL-C) from whole blood. More specifically, it relates to a process for making a microporous plasmapheresis membrane having an immobilized affinity agent. The immobilized affinity agent is polyacrylic acid bound directly and/or through an interaction with silica and/or calcium chloride to a microporous hollow fiber membrane.

High efficiency removal of low density lipoprotein-cholesterol from

The present invention relates to the efficient removal of low density lipoprotein cholesterol complex (LDL-C) from whole blood. More specifically, it relates to a microporous plasmapheresis support having an immobilized affinity agent. The immobilized affinity agent is polyacrylic acid bound directly and/or through an interaction with silica and/or calcium chloride to a microporous polysulfone support.

Microporous polysulfone supports suitable for removal of low density

A battery separator composed of a microporous sheet product having first and second major surfaces and a thickness of less than about 50 mils, formed from a uniform mixture of a polysulfone polymer and a filler or polysulfone polymer and structure enhancing agent, said sheet product having a fibrous sheet embedded within said mixture and between the first and second major surfaces. The porosity of the sheet product is at least about 60 volume percent composed of pores such that the average pore diameter increases from each major surface toward the interior of the sheet product's thickness.

Battery separator

A battery separator composed of a microporous sheet product having first and second major surfaces and a thickness of less than about 50 mils, formed from a uniform mixture of a halogenated polyolefin polymer and a filler or a halogenated polyolefin polymer and surfactant/filler agent, said sheet product having a fibrous sheet embedded within said mixture and between the first and second major surfaces. The porosity of the sheet product is at least about 50 volume percent composed of pores such that the average pore diameter increases from each major surface towards the interior of the sheet product's thickness.

A battery separator composed of a microporous sheet product having first and second major surfaces and a thickness of less than about 50 mils, formed from a uniform mixture of a polycarbonate polymer and a filler or a polycarbonate and a structure enhancing agent, said sheet product having a porous sheet embedded within said mixture and between the first and second major surfaces. The porosity of the sheet product is at least about 50 volume percent composed of pores such that the nominal pore diameter increases incrementally from each major surface towards the interior central portion of the sheet product's thickness.

A battery separator composed of a microporous sheet product having first and second major surfaces and a thickness of less than about 50 mils, formed from a uniform mixture of a polymer and a filler or a polymer and a structure enhancing agent and having a porous sheet embedded between the first and second major surface. The porosity of the sheet product is at least about 50 volume percent having a pore distribution such that the nominal pore diameter increases from each major surface towards the interior central portion of the sheet product's thickness.

A battery separator composed of a microporous sheet product having first and second major surfaces and a thickness of less than about 50 mils, formed from a uniform mixture of a thermoplastic polyurethane polymer having a high degree of hard segments with a filler or said polyurethane with a structure enhancing agent, said sheet product having a sheet embedded within said mixture and between the first and second major surfaces. The sheet product has porosity of at least about 50 volume percent composed of pores such that the nominal pore diameter increases from each major surface towards the interior, center of the sheet product's thickness.

Microporous polyurethane based battery separator

Process of making a membrane for high efficiency removal of low density

The present invention relates to the efficient removal of low density lipoprotein cholesterol complex (LDL-C) from whole blood. More specifically, it relates to the use of an immobilized affinity agent on a microporous plasmapheresis membrane. The immobilized affinity agent is polyacrylic acid bound directly and/or through an interaction with silica and/or calcium chloride to a microporous hollow fiber membrane.

Process of making membrane for removal of low density

Membrane having high affinity for low density lipoprotein-cholesterol

A diagnostic assay support matrix is prepared by coating a support matrix with a polymer resistant to nonspecific protein binding and immobilizing the desired biologically active agent on the polymer surface.

Growing community of inventors

Bedford, MA, United States of America

Marc E Parham