Duke University

Marc Deshusses

Bruce Klitzman

Ira Cheifetz

Tobias Straube

Travis Vesel

Stewart Farling

Yaacov Nagar

Kurabachew Duba

Kathleen Jooss

The present disclosure describes intravascular oxygenation systems and methods with one or more of improved oxygen diffusion flux, improved resistance to bubble formation on the surface of non-porous hollow fibers, and reduced size. The systems and methods include a pneumatic inlet coupled to a pneumatic source that provides a gas containing oxygen at a high pressure. A plurality of hollow fiber membranes (HFM) are in pneumatic communication with the pneumatic inlet to receive the gas containing oxygen and with an outlet to exhaust a partially deoxygenated gas. An electronic controller drives the motor to oscillate the plurality of HFMs to cause a diffusive flux of the gas containing oxygen from the plurality of HFMs into a region of interest of a subject. The electronic controller may drive the motor according to an oscillation pattern, which may include a macro-oscillation with superimposed micro-oscillations.

Intravascular membrane oxygenator catheter with oscillating hollow fiber membranes

A waste processing system includes a reactor including an inlet end and an outlet end configured to discharge reactor effluent. The inlet end includes a mixing unit having an oxidizing material input and a waste stream input. The reactor oxidizing material input is configured to receive reactor oxidizing material at a temperature greater than 200&#xb0; C. and at a pressure greater than 60 atm. A second waste stream input is positioned between the reactor inlet end and the reactor outlet end.

Systems, methods, and techniques for waste processing

Growing community of inventors

Durham, NC, United States of America

Marc Deshusses