Xendo Holding B.v.

Axellia Pharmaceuticals Aps

Cooperatie Avebe U.a.

Syngen Biotech, Co., Ltd.

Marc Antonius Theodorus Bisschops

Marco Luigi Federico Giuseppin

Lene Aassveen

Jacob Arthur Tijsterman

Anita Mathiesen

Tiemen Geert Pieter Reijns

Jozef Anton Mari Pennings

Tiem Geert Pieter Reijns

A method and system is provided for yielding biopharmaceutical products involving a chromatographic separation process. The method comprises: providing a plurality of membrane adsorber cartridges; providing a plurality of valves, communicatively coupled to said plurality of membrane adsorber cartridges; and switching the valves, so as to interconnect said membrane adsorber cartridges to operate in a countercurrent flow mode. The system comprises multiple membrane adsorber cartridges that are interconnected and configured to operate in a countercurrent flow mode. Furthermore, the configuration comprises a valve assembly that allows the cartridges to be subjected to different steps in the process by automatic switching of the valves. In this way, cartridges are recycled many times during the purification of a batch.

Method and device for continuous membrane adsorption

A method for purification of the antibiotic mupirocin (pseudomonic acid A) which comprises: a) Causing or allowing precipitation of mupirocin from an aqueous solution thereof; b) Recovering the precipitate; c) Dissolving the recovered precipitate in an organic solvent.

Purification of mupirocin

Growing community of inventors

Breda, Netherlands

Marc Antonius Theodorus Bisschops