Solvay (societe Anonyme)

Solvay Sa

Solvay & Cie (societe Anonyme)

Solvay

Marc Anteunis

Roland Callens

Georges Blondeel

Frank Becu

Christian Becu

Ureins are obtained by reaction, in basic medium, between an N-(aryloxycarbonyl)diamino acid and a compound containing a free amino group. The chirality of the compounds is outstandingly well preserved.

Ureins derived from &#x3b1;, &#x3c9;, diamino acids and process for their preparation

Ureins are obtained by reaction, in basic medium, between an N,-(aryloxycarbonyl)diamino acid and a compound containing a free amino group. The chirality of the compounds is outstandingly well preserved.

Ureins derived from &agr;, &ohgr;-diamino acids and process for their preparation

Ureins are obtained by reaction, in basic medium, between an N.sup..omega. -(aryloxycarbonyl)diamino acid and a compound containing a free amino group. The chirality of the compounds is outstandingly well preserved.

Ureins derived from alpha, omega-diamono acids and process for their

Compounds having the general formula: ##STR1## in which R3 represents an aryl group which is unsubstituted or substituted by one or more alkyl groups containing 1 to 4 carbon atoms; R4 represents a hydrogen atom, a group for protecting the amino functional group, an amino acid or a peptide some of whose functional groups are optionally substituted by a protecting group or by an activating group; R5 represents a hydroxy group, a halogen atom, a group for protecting the carboxyl functional group, an activating group, an amino group, an amino acid or a peptide some of whose functional groups are optionally substituted by a protecting group or by an activating group; and n is an integer from 1 to 10.

N-aryloxycarbonyl amino acids and peptides and their derivatives

The process enables peptides to be synthesized from amino acids with the participation of trialkylcyanosilanes. The peptides obtained by this synthesis route are used, in particular, in pharmaceutical applications.

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Mariakerke, Belgium

Marc Anteunis