Smithkline Beecham Corporation

Glaxosmithkline LLC

Janssen Pharmaceuticals, Inc.

Maosheng Duan

Wieslaw Mieczyslaw Kazmierski

Beth Adams Norton

Pingyun Chen

Ricky Wayne Couch

Christopher Joseph Aquino

Matthew Tallant

Pek Yoke Chong

Eric Eugene Boros

Jennifer Poole Peckham

Richard Martin Grimes

James Benjamin Thompson

Cecilia Suarez Koble

Neil Bifulco, Jr

Felix Deanda, Jr

Ed Williams McLean

Angilique C Perkins

Dana Vanderwall

Pek Yeng Chong

Chrisopher Joseph Aquino

Brian Andrew Chauder

Disclosed are compounds of Formula III. Also disclosed are salts of the compounds, pharmaceutical composition comprising the compounds or salts, and methods for treating HCV infection by administration of the compounds or salts. 

Chemical compounds

The present invention relates to compounds of Formula (I) and (Ia) useful in the treatment of CCR5-related diseases and disorders, for example, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).

Therapeutic compounds

The present invention relates to compounds of formula (I) or a pharmaceutically acceptable derivatives thereof, useful in the treatment of prophylazis of CCR5-related diseases and disorders, for example, in the inhibition of HIV replication, the prevention or treatment of HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).

CCR5 antagonists as therapeutic agents

The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).

Cyclohexyl compounds as CCR5 antagonists

Heterocyclic compounds as CCR5 antagonists

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Durham, NC, United States of America

Maosheng Duan