Shenyang Pharmaceutical University

Jinzhou Jiutai Pharmaceutical Co., Ltd., China

Maosheng Cheng

Jianmin Shen

Guilan Song

Lie Ji

Li Pan

Li Zhang

Zhiging Li

The invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein Ris H, chlorine, or bromine; Ris electron attractive groups selected from the group consisting of CF, CN, fluorine, CHSO, CFSO, and NO; Ris linear or branched alkyl having 1 to 10 carbon atoms, linear or branched alkoxyalkyl having 2 to 10 carbon atoms, aliphatic alcohol having 1 to 10 carbon atoms, or cycloalkyl having 3 to 6 carbon atoms. The invention also relates to methods for preparing the said compounds and the composition comprising the same. The compounds of the present invention have the effect of &#x3b2;-receptor agonist and can be used for the treatment of asthma and bronchitis 

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Shenyang, China

Maosheng Cheng