Amazon Technologies, Inc.

Manuela Alanis

William Greger

Aida Martin Galan

Emanuel Elizalde

Luciano Braggio

Bruno Nicolas Bavaresco Elissetche

Ryan Patrick Rafter

Andrea Larsen

Mark Patrick Kreuzer

Matias Ezequiel Andreoli

Biological sample processing system assemblies include a swab chamber assembly configured to enhance transfer of a biological sample on a swab head to a resulting biological sample solution for subsequent processing. A swab chamber assembly includes a fluid channel and an elongated swab chamber having a proximal portion and a distal portion. The swab chamber is configured to accommodate insertion of a swab head of a swab into the swab chamber. The distal portion of the swab chamber slopes downwardly from a distal end of the proximal portion of the swab chamber so that lysis buffer solution transferred into the swab chamber accumulates within the distal portion of the swab chamber.

Biological sample processing assemblies and methods

Diagnostic testing systems and related methods employ actuation pressure-based control during fluid transfer within a test cartridge. A method of operating a cartridge to process a biological sample includes coupling an actuation port of the cartridge with a pump assembly of a portable analyzer. A transfer operation of the pump assembly induces airflow through the actuation port so as to displace an aliquot of the sample solution along a fluid channel. A control unit monitors a pressure signal indicative of a pressure of air displaced by the pump assembly. The transfer operation is stopped in response to a change in the pressure signal indicative of contact of the aliquot of the sample solution with a hydrophobic staging vent.

Microfluidic systems and methods

Single use cartridges for testing biological samples are provided that include multiple processing channels. A single use cartridge includes an aliquot staging well, a first amplification well, a second amplification well, an actuation port, and a fluid channel control valve assembly. The fluid channel control valve assembly is reconfigurable between a first fluid channel configuration and a second fluid channel configuration.

Assay cartridge

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Buenos Aires, Argentina

Manuela Alanis