Novartis Ag

Manuel Mihalic

David Jonathan Glass

Simone Bonazzi

Andrew William Patterson

Silvio Roggo

Tea Shavlakadze

Michael Connolly

Patrik Zueger

The disclosure provides 32-deoxo-rapamycin derivatives of Formula (I), or a pharmaceutically acceptable salt thereof, pharmaceutical compositions and pharmaceutical combinations comprising a compound of Formula (I), and methods of making same. Also provided herein are methods of using a compound of Formula (I) or a pharmaceutically acceptable salt thereof for treating the diseases and disorders described herein.

Rapamycin derivatives

Growing community of inventors

Munich, Georgia

Manuel Mihalic