Medical 21, Inc.

Manuel A Villafana

Chaid D Schwarz

Eric E Solien

Jeff R Vreeman

A composite implant having multiple open-pore biodegradable polymer layers mechanically supported by a permanent structure positioned between adjacent polymer layers drives a native response for cellular infiltration, which facilitates progressive cellular-driven remodeling, cellular organization, and native extra-cellular matrix (ECM) deposition. This leads to endogenous tissue remodeling of the implant over time. The support structure provides mechanical support to the implant to effectively carry impressed mechanical load while the remodeling process is ongoing. The polymer layers are formulated to fully degrade over time, leaving only the new native tissue supported by the permanent support structure.

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Wayzata, MN, United States of America

Manuel A Villafana