Health Research, Inc.

Zhejiang Hisun Pharmaceutical Co., Ltd.

Photolitec, LLC

Manivannan Ethirajan

Ravindra Kumar Pandey

Hua Bai

William G Cance

Anurag Gupta

Zhenliang Chen

Nayan Patel

Elena V Kurenova

Penny Joshi

Avinash Srivatsan

Disclosed are a cyanine dye compound and a preparation method therefor, and a dual-function agent for photodynamic therapy and a preparation method therefor. The provided cyanine dye compound is connected to multiple markers, which improves the accuracy of combination of dye and tumor cells, effectively reduces the background value, and avoids excessive residues in the liver. The provided cyanine dye compound is conjugated with the photosensitizer at 2'&#x2033; position, so that tumor highly absorbs the conjugates.

Cyanine dye compound and preparation method therefor, and dual-function agent for photodynamic therapy and preparation method therefor

The invention relates to protein binding inhibitor compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating cell proliferative disorders, especially cancer.

Kinase protein binding inhibitors

A tetrapyrrolic photosensitizer and imaging compound having a substituent other than hydrogen at its 10 carbon atom which substituent may contain a PAA nanoparticle.

PAA nanoparticles for tumor treatment and imaging

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Cheektowaga, NY, United States of America

Manivannan Ethirajan