Wockhardt Limited

Manish Solanki

Bharat Kalidas Trivedi

Mahesh Vithalbhai Patel

Prasad Keshav Deshpande

Sachin Subhash Bhagwat

Ravikumar Tadiparthi

Shivaji Sampatrao Pawar

Amit Chandra Mishra

Mohammad Alam Jafri

Sunil Gupta

Deepak Dekhane

Satish Bhavsar

Santosh Diwakar

Vijay Patil

Bharat Trivedi

The invention relates to ketolide compounds of Formula (I) and their pharmaceutically acceptable salts, solvates, hydrates, polymorphs and stereoisomers having antimicrobial activity. The invention also provides pharmaceutical compositions containing the compounds of invention and methods of treating or preventing microbial infections with the compounds of invention, wherein, T is &#x2014;C*H(R)&#x2014;P-Q; Ris hydrogen; unsubstituted or substituted lower alkyl, cycloalkyl or aryl; P is heteroaryl ring; Q is unsubstituted or substituted aryl or heteroaryl ring; and P is attached to Q via carbon-carbon link; and Ris hydrogen or fluorine, With the provision that when Ris hydrogen, Ris fluorine. 

Ketolide compounds

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Aurangabad, India

Manish Solanki