Other

Netra Systems, Inc.

Manish Dinkarrao Kulkarni

Joseph A Izatt

Michael V Sivak

Manmohan Singh Sidhu

Andrew M Rollins

Siavash Yazdanfar

Piyush Gupta

Shuqing Ma

Balasigamani Devaraj

There is a need for robust and portable system, and apparatus for ophthalmology. We propose use of foldable ophthalmic system. Our system will have a chin-rest (or face-rest or forehead rest) that can be folded so that the ocular device could be transported in a brief-case type casing. Our system can be used for many modalities including optical coherence tomography.

Foldable and portable ocular systems

There is a need for robust and portable system, apparatus and method for imaging subsurface of specimens. We have described a modular OCDR-OCT system and OFDR-OCT system to obtain high quality images. The instant application also discusses proprietary algorithms that have been modified from existing algorithms and their use as a combination to suit a particular system. The imaging of stationary, moving and combination of both subsurface structures such as retina for diabetic patients is described.

System and method for imaging subsurface of specimen

Foldable ophthalmic system

Optical Coherence Tomography (OCT) system and apparatus of this instant application is very useful for diagnosis and management of ophthalmic diseases such as retinal diseases and glaucoma etc. Instant innovative OCT diagnostic system leverages advancements in cross technological platforms. The Michelson interferometric system presented in this application could be used for the OCT imaging, which includes biological OCT imaging, medical OCT imaging, ophthalmic OCT imaging, corneal OCT imaging, retinal OCT imaging, and the like. A tunable filter is placed in front of the detector to make the interferometer more sensitive and accurate for examining various samples for diagnosis.

Method and system for low coherence interferometry

There is a need for robust and portable system, and apparatus for ophthalmology. We propose use of folding apparatus for ocular purposes for the first time. Our system will have a chin-rest (or face-rest or forehead rest) that can be folded so that the ocular device could be transported in a brief-case type casing.

Compact foldable apparatus for ophthalmology

We hereby report a location specific mobile messaging system. These messages could be displayed (by way of example but not by limitation) in a location viewable by a variety of people. The contents of these messages could be programmed to display messages specific to a location.

Mobile location and time sensitive messaging platform

The system disclosed is for optical coherence tomography (OCT). The system includes an improved interferometric system for metrology, detection, ranging as well as imaging system based on optical coherence tomography (OCT). Further, the method provides advancements in detection, imaging of samples in biological, medical, ophthalmic, corneal and retinal diagnosis.

Compact, affordable optical test, measurement or imaging device

A method for generating a velocity-indicating, tomographic image of a sample in an optical coherence tomography system includes the steps of (a) acquiring cross-correlation data from the interferometer; (b) generating a grayscale image from the cross-correlation data indicative of a depth-dependent positions of scatterers in the sample; (c) processing the cross-correlation data to produce a velocity value and location of a moving scatterer in the sample; (d) assigning a color to the velocity value; and (f) merging the color into the grayscale image, at a point in the grayscale image indicative of the moving scatterer's location, to produce a velocity-indicating, tomographic image. Preferably a first color is assigned for a positive velocity value and a second color is assigned for a negative velocity value.

Doppler flow imaging using optical coherence tomography

A method is described for determining depth-resolved backscatter characteristics of scatterers within a sample, comprising the steps of: acquiring a plurality of sets of cross-correlation interferogram data using an interferometer having a sample arm with the sample in the sample arm, wherein the sample includes a distribution of scatterers therein, and wherein the acquiring step includes the step of altering the distribution of scatterers within the sample with respect to the sample arm for substantially each acquisition; and averaging, in the Fourier domain, the cross-correlation interferogram data, thereby revealing backscattering characteristics of the scatterers within the sample.

Depth-resolved spectroscopic optical coherence tomography

The present invention provides an improved optical coherence tomography system and involves estimating the impulse response (which is indicative of the actual reflecting and scattering sites within a tissue sample) from the output interferometric signal of an interferometer according to the following steps: (a) acquiring auto-correlation data from the interferometer system; (b) acquiring cross-correlation data from the interferometer system having the biological tissue sample in the sample arm; and (c) processing the auto-correlation data and the cross correlation data to produce an optical impulse response of the tissue. The impulse response may be obtained from the cross-correlation and auto-correlation data by: (d) obtaining an auto-power spectrum from the auto-correlation data by performing a Fourier transform on the auto-correlation data; (e) obtaining a cross-power spectrum from the cross-correlation data by performing a Fourier transform on the cross-correlation data; (f) obtaining a transfer function of the LSI system by taking a ratio of the cross-power spectrum to the auto-power spectrum; and (g) obtaining the optical impulse response of the LSI system by performing an inverse-Fourier transform on the transfer function. Preferably, coherent demodulation is used in combination with the above deconvolution technique to resolve closely-spaced reflecting sites in the sample. By utilizing both the magnitude and phase data of the demodulated interferometric signals, the OCT system of the present invention is able to distinguish between closely spaced reflecting sites within the sample.

Growing community of inventors

Pleasanton, CA, United States of America

Manish Dinkarrao Kulkarni