Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V.

Richard Wolf Gmbh

Technische Universitaet Dresden

Saxonia R + D Gmbh & Co. Kg

Urotec Gmbh

Urotiss Gmbh

Manfred Wirth

Friedemann Horn

Jörg Hackermüller

Sabina Christ

Kristin Reiche

Michael Fröhner

Susanne Füssel

Bernd Claus Weber

Klaus Müller

Larry Purcell

Stephan Sieber

Ursula Ravens

Gouya Ram-Liebig

Stefan Gille

Rainer Koch

Susanne Fuessel

Matthias Lambertz

Rudolph Lüning

Manfred Weigel

Oliver Hakenberg

A light applicator () for examining and/or treating an organic body includes a minimal-invasive, rigid, semi-flexible or flexible insertion section () which extends along a longitudinal direction (L) and at its distal end includes an LED (). The light applicator () includes a first electrical lead () for the supply of electricity to the LED (). The lead extends in the insertion section () in the longitudinal direction (L) and there has a cross-sectional area of at least 70% of the cross-sectional area of the light applicator (). The light applicator () in the insertion section () is thermally insulated in the radial direction in a manner such that the radial thermal insulation reduces proximally.

Light applicator

The invention relates to urinary catheters having a catheter tube with a first connection on the distal end and at least one catheter eye to be positioned in the urinary bladder. The urinary catheters are distinguished in particular in that they may be used problem-free as indwelling catheters. To this end, disposed in the urinary bladder is a reservoir container that is connected via a channel running parallel to the catheter tube to a second connection as distal end of the channel. In addition, the channel is connected to the urethra via at least one opening of the channel wall.

Urinary catheter

The invention relates to the identification and selection of differentially expressed transcripts (biomarker) in tumor cells. Specific determination of the level of these biomarkers can be used for screening and diagnosis of prostate cancer. Clinical application of assays based on these biomarker help reduce the high number of false positives of current standard screening assays.

RNA-biomarkers for diagnosis of prostate cancer

RNA-biomarkers for diagnosing prostate cancer

The invention relates to the identification and selection of differentially expressed transcripts (biomarker) in tumour cells. Specific determination of the level of these biomarkers can be used for screening and diagnosis of prostate cancer. Clinical application of assays based on these biomarker help reduce the high number of false positives of current standard screening assays.

The present invention relates on a non-invasive method for diagnosing prostate cancer and/or assessing the risk of a subject acquiring prostate cancer comprising the analysis of the expression of the marker gene hepsin in an urine sample. It further relates on a non-invasive method for diagnosing prostate cancer and/or assessing the risk of a subject acquiring prostate cancer by determining the expression levels of the marker genes hepsin, EZH2, prostein and PCA3.

Non-invasive method for diagnosis of prostate cancer

A process for producing a tissue transplant construct for reconstructing a human or animal organ. The process may include the steps of: (a) isolation and two-dimensional cultivation of organ-specific tissue cells; (b) application of the organ-specific tissue cells to a biocompatible, collagen-containing membrane; and, (c) cultivation of the organ-specific tissue cells on the membrane with biochemical and mechanical stimulation of the organ-specific tissue cells. Tissue transplant constructs and methods for using tissue transplant constructs are also taught.

Process for producing a tissue transplant construct for reconstructing a human or animal organ

Growing community of inventors

Dresden, Germany

Manfred Wirth