The United States of America, As Represented by the Secretary, Department of Health and Human Services

Juno Therapeutics Gmbh

Sitkovsky, Michail V.

Manfred Thiel

Michail V Sitkovsky

Methods for modulating responsiveness to increased oxygen levels in an at-risk subject identifying an at-risk subject; and before exposing the identified at-risk subject to an increased amount of oxygen, administering to the at-risk subject an anti-inflammatory agent wherein the responsiveness of the at-risk subject to said increased amount of oxygen is modulated as compared to the responsiveness of the at-risk subject to said increased amount of oxygen in the absence of said anti-inflammatory.

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Eichenau, Germany

Manfred Thiel