Physion S.r.l.

Dr.r.pfleger Chemische Fabrik Gmbh

Manfred Stohrer

Robert L Stephen

Cino Rossi

Silvio Eruzzi

Franco Lugnani

Umberto Fontanella

Donald P Griffith

Albert Schaupp

Augustinus Kramer

Ulrich Schwantes

Compositions of the anticholinergic agent trospium chloride suitable for localized administration are provided, in the form of an aqueous solution having a pH-value of.gtoreq.4.5, that is prepared prior to administration. Methods of using the provided compositions for treating dysfunctions of the bladder and the urinary system are also provided. The treatment methods are characterized by the intravesicular administration of the inventive composition into the bladder of a patient in need thereof

Use of trospium chloride and 2-component system for the same

A method of treating acute urinary outflow system obstruction caused by disease of the prostate gland by localised electromotive drug administration. The treatment comprises insertion within the prostatic urethra and within the bladder cavity of a urethral catheter which incorporates a specific electrode and is adapted to perform the electromotive administration of a drug or drug mixture into diseased prostatic tissues thereby resolving the pathologies without resorting to surgery.

Electromotive drug administration for treatment of acute urinary outflow

An intravesical method of treating dysfunctional bladder syndromes by Electromotive Drug Administration (EMDA) of local anaesthetic drugs, anti muscarinic drugs and sympathomimetic agents. The administration of said drugs combined with hydraulic bladder dilatation causes relaxation of the detrusor muscle, reversing the hypertonicity associated with dysfunctional bladder syndromes.

Method of treating dysfunctional bladder syndromes by electromotive drug

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Murnau, Germany

Manfred Stohrer