Universitat Ulm

Edi Gmbh

Hot Screen Gmbh

Edi (experimentelle & Diagnostische Immunologie) Gmbh

Rules-based Medicine, Inc.

Schmolz, Dr., Manfred

Manfred Schmolz

Marion E Schneider

Rolf Kaufmann

Günther Uhr

The present invention refers to a cell culture system especially for investigating the sensitizing, allergenic and/or irritating effect of substances, comprising a first and a second compartment that can communicate with each other via a permeable interlayer, whereby the first compartment has an epidermis model and the second a cell culture based on immune cells.

Cell culture system for determining the sensitizing, allergenic and/or irritating effect of a substance

The present invention refers to a method for recognizing and/or characterizing cellular activity patterns, in particular for diagnostic purposes and/or for tracking the therapy of diseases. Blood cells are stimulated in a culture medium at least with toll-like receptor ligands (TLR ligands) and the stimulated blood cells and/or the culture medium are examined.

ILCS based pattern recognition of sepsis

The invention relates to a method for the determination of the immune defence activity of blood by the stimulation of white cells in the whole blood, incubation of the whole blood, separation of the supernatant from the sediment and determination of the activity from the separated supernatant. he invention also relates to a test kit for performing the method and to the use of a suitable blood sampling system, particularly a syringe cylinder for this purpose.

Method for determining the immune defense of blood and test kit for the same and use of a suitable blood sampling system

Growing community of inventors

Reutlingen, Germany

Manfred Schmolz