Dr. Karl Thomae Gmbh

Karl Thomae Gmbh

Boehringer Ingelheim Gmbh

Boehringer Ingelheim Kg

Celamerck Gmbh & Co. Kg

Dr. Karl Thomae Gesellschaft MIT Beschrankter Haftung

Manfred Reiffen

Norbert Hauel

Joachim Heider

Volkhard Austel

Wolfgang Grell

Willi Diederen

Robert Sauter

Rudolf Hurnaus

Eckhard Rupprecht

Walter Kobinger

Jacobus C Van Meel

Christian Lillie

Klaus Reinhold Noll

Gerhart Griss, Deceased

Berthold Narr

Michael Entzeroth

Andreas Bomhard

Walter Haarman

Armin Heckel

Wolfgang Eberlein

Wolfgang Wienen

Michael Mark

Helmut Pieper

Uwe Joerg Ries

Josef Nickl

Ludwig Pichler

Johannes Keck

Joachim Mierau

Gerd Kruger

Gunter Schingnitz

Jacques Van Meel

Jurgen Dammgen

Manfred Psiorz

Rudolph Hurnaus

Gerhart Griss

Eckhard Ruprecht

Phenylacetic acid benzylamides having the following general structure

Phenylacetic acid benzylamides

The present application relates to the uses of phenylacetic acid benzylamides and new (S)(+)-2-ethoxy-4-[N-[1-2-piperidino-phenyl)-3-methyl-1-butyl]-aminocarbon ylmethyl]-benzoic acid and the salts thereof, which have valuable pharmacological properties, namely an effect on the intermediate metabolism, but particularly the effect of lowering blood sugar.

Substituted thiazoles, oxazoles and 2-hydroxy morpholine compounds useful in the treatment of diabetes mellitus and obesity are described.

Substituted thiazoles and oxazoles and 2-hydroxy-morpholines

A phenylalkyl derivative of the formula ##STR1## wherein R.sub.a to R.sub.f, A and B are substituents and n is the number 0 or 1. These phenylalkyl derivatives possess angiotensin antagonist activity.

Phenylalkyl derivatives, with pharmaceutical activity

Compounds of formula ##STR1## where the substituents are as defined herein, are disclosed, which compounds are useful in the treatment of diabetes and obesity, among other uses.

Substituted thiazoles useful for treatment of diabetes

The present application relates to the uses of phenylacetic acid benzylamides and new (S)(+)-2-ethoxy-4-[N-[1-2-piperidino-phenyl)-3-methyl-1-butyl]-aminocarbon ylmethyl]benzoic acid and the salts thereof, which have valuable pharmacological properties, namely an effect on the intermediate metabolism, but particularly the effect of lowering blood sugar.

Phenylethanolamines, their use as pharmaceuticals and as performance

Substituted thiazoles and oxazoles and pharmaceutical compositions and

Phenylacetic acid benzylamides having the following general structure ##STR1## wherein the substituents are defined herein, are disclosed, which compounds are hypoglcemic agents.

Disclosed are new cyclic amine derivatives of the formula I ##STR1## wherein the substituents are defined in the specification. These compounds are useful as for treating sinus tachycardia.

Cyclic amine derivatives, pharmaceutical compositions containing these

The present invention relates to new 4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepines of general formula II ##STR1## wherein the substituents are defined herein below, which compounds have valuable pharmacological properties, namely selective effects on the dopaminergic system which are achieved by stimulating (predominantly D2) dopamine receptors.

4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepines, their preparation and

The invention relates to new morpholines and morpholine-N-oxides of formula ##STR1## wherein the substituents are defined hereunder, which compounds have valuable pharmacological properties, namely an effect on the metabolism, preferably the effect of lowering blood sugar and reducing body fat, and the effect of lowering the atherogenic .beta.-lipoproteins VLDL and LDL, and a performance enhancing effect in animals.

Morpholines and morpholine-N-oxides and pharmaceutical compositions

Compounds of the formula ##STR1## wherein A, B, C and D are --N.dbd., HN.dbd., R.sub.3 N.dbd., O.dbd.C.dbd., HC.tbd., HO--C.tbd. or R.sub.3 SO.sub.2 --O--C.tbd.; and

2-phenyl-imidazopyridin-ones and also useful as cardiotonics and

Compounds of the formula ##STR1## wherein A, B, C and D are each independently --N.dbd. or --CH.dbd., provided, however, that at least two of them must be --N.dbd., and when A and C are both --N.dbd., at least one or both of B and D must be --N.dbd.; and

2-phenyl-imidazo-pyrazines, -pyridazines and -triazines

Growing community of inventors

Biberach, Germany

Manfred Reiffen