Koninklijke Philips Corporation N.v.

Manfred Muller

Christian Reich

Bernardus Hendrikus Wilhelmus Hendriks

Gerhardus Wilhelmus Lucassen

Robert Johannes Frederik Homan

Jeroen Jan Lambertus Horikx

Nicolaas Jan Noordhoek

Rami Nachabe

Payal Keswarpu

Arnoldus Theodorus Martinus Hendrics Van Keersop

Vipin Gupta

The invention relates to an apparatus for determining a property of a tissue, particularly cancer of cervical tissue. A light providing unit () provides light for illuminating the tissue () and a light detection unit () detects light from the tissue, wherein a first signal being indicative of light () having been influenced by an epithelium region (R), a second signal being indicative of light () having been influenced by a boundary region (R) and a third signal being indicative of light () having been influenced by a stroma region (R) are generated, and wherein a tissue property is determined based on the first, second and third signals. This allows for an determination of a tissue property, which is based on a combination of optical properties measured in the three different regions, resulting in an improved determination of the tissue property, in particular in improved cancer detection.

Apparatus for determining a property of a tissue

The present invention relates to a system () for navigating and positioning an instrument () in a body (). The instrument () is detectable by the system () and the system () displays a view to an operator. The instrument () is adapted to identify tissue parameters. The system () is adapted to display an image being a combined image of the interior of a body () and an indication of the tissue parameter at the appropriate earlier locations. The present invention further relates to a method () including determining tissue parameters and displaying the parameters in an image of a body (). The present invention further relates to a software implemented method () for being executed on a digital processor. The present invention further relates to an instrument ().

Integration delayed optical feedback in image guidance

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Eindhoven, Netherlands

Manfred Muller