Leica Instruments (singapore) Pte. Ltd.

Leica Microsystems (schweiz) Ag

Storz Endoskop Gmbh

Storz Endoskop Produktions Gmbh

Leica Instruments Pte. Ltd.

Manfred Kuster

Beat Krattiger

Harald Haan

George Themelis

Pavel Novak

Heinz Suhner

Michael Guentert

Martin Klumpp

J&ouml;rg Reling

Ulrich Sander

Harald Schnitzler

Haw Chong Soon

Peter Strobel

Marco Schutz

Marc Hocke

Ralf Körber

Ralf Koerber

James Ng

Luca Tobler

Heinrich Wilhelm Dreyer

Patrick Wolf

The present invention relates to an illumination filter system () for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope () or endoscope, such as a surgical microscope, in particular a surgical multispectral fluorescence microscope, comprising a first optical filter (). The present invention also relates to an observation system () for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope () or endoscope, in particular a multispectral fluorescence microscope, comprising a beam splitter () adapted to split a light image () into a first light portion () along a first light path () and a second light portion () along a second light path (). To improve known illumination filter systems and observation systems, so these systems work with one light source only, are capable of capturing simultaneously at least one fluorescence signal and a signal of visible reflected light and allow a homogeneous illumination for obtaining different images from the object illuminated, the first optical filter () is adapted to quench light of at least one fluorescence excitation band within the visible spectrum in the illumination filter system () of the present invention, and the first light portion () comprises at least one fluorescence emission band (Em., Em.) in the visible spectrum and the second light portion () portion comprises a visible reflected light (VISR) in the observation system () of the present invention.

Illumination filter system and observation system for a multispectral fluorescence microscope, multispectral fluorescence microscope, and microscopying method

A beam splitter device () for a microscope (), and for a microscope imaging method, supports at least two beamsplitting surfaces (). The two beamsplitting surfaces () have different reflection-to-transmission ratios. The beam splitter device () has an optical path (). A first one of the two beamsplitting surfaces () is configured to be moved from a first operation position (), in which the first beamsplitting surface () is located in the optical path, to a second operation position (), in which a second () of the beamsplitting surfaces () is located in the optical path. With this configuration, it is possible to change the available light in the branches () of the optical path () after the beamsplitting surface (). This is useful if one of the branches () is directed to an exit port () configured to receive a camera. By directing more light to the camera exit port (), the image quality of the camera is improved.

Beam splitter device having at least two beamsplitting surfaces with different reflection-to-transmission ratios

The present invention relates to an illumination filter system () for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope () or endoscope, such as a surgical microscope, in particular a surgical multispectral fluorescence microscope, comprising a first optical filter (). The present invention also relates to an observation system () for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope () or endoscope, in particular a multispectral fluorescence microscope, comprising a beam splitter () adapted to split a light image () into a first light portion () along a first light path () and a second light portion () along a second light path (). To improve known illumination filter systems and observation systems, so these systems work with one light source only, are capable of capturing simultaneously at least one fluorescence signal and a signal of visible reflected light and allow a homogeneous illumination for obtaining different images from the object illuminated, the first optical filter () is adapted to quench light of at least one fluorescence excitation band within the visible spectrum in the illumination filter system () of the present invention, and the first light portion () comprises at least one fluorescence emission band (Em.1, Em.2) in the visible spectrum and the second light portion () portion comprises a visible reflected light (VISR) in the observation system () of the present invention.

An illumination and observation system () for an ophthalmic surgical microscope () has first, second, third and fourth observation pupils () for two observers, a coaxial illumination () in the first, third and fourth observation pupils to generate a red reflex () therein, and a main illumination () in the second observation pupil. For widely illuminating the surroundings, the main illumination has a larger illumination field than the coaxial illumination in any of the first, third and fourth observation pupils. For superior observation quality and a visible and homogenous red reflex in the second observation pupil, the main illumination overlaps at least 50% with the second observation pupil. The main illumination may be aligned within &#xb1;5&#xb0; to an optical axis () of the second observation pupil and to overlap the coaxial illumination at least 50% with the first, third and fourth observation pupils.

Illumination and observation system for an ophthalmic microscope, ophthalmic microscope and microscopying method using four red reflex observation pupils

An illumination and observation system (), in particular for an ophthalmic microscope, comprises a first observation pupil () and a second observation pupil () for the eyes of an observer such as an assistant. Further, the system comprises a coaxial illumination () in the first observation pupil () and a main illumination (), the coaxial illumination () being adapted to generate a red reflex () in the observed eye in operation and the main illumination having a larger field of illumination than the coaxial illumination (). To facilitate usage of the system () and/or the microscope () and to create a superior stereoscopic view using the red reflex (), a control subsystem () is provided which is adapted to automatically adjust an intensity of the main illumination () depending on a change in an intensity of the coaxial illumination ().

Illumination and observation system for an ophthalmic microscope, ophthalmic microscope comprising such a system, and microscopying method

The invention relates to an illumination unit that encompasses two light sources arranged one behind another in a channel . A cooling unit is provided respectively at the two ends of the channel. The invention further relates to an energy supply unit for supplying the illumination unit with electrical energy. The energy supply unit encompasses two energy sources arranged in a channel. Respective cooling units are arranged at the two ends of the channel.

Illumination unit for medical devices, and energy supply unit for supplying the illumination unit with electrical energy

The invention relates to an illumination filter () for an illumination filter system () for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope () or endoscope, in particular a multispectral fluorescence microscope. The present invention provides an illumination filter for medical imaging, in particular a multispectral fluorescence imaging, that is capable of capturing simultaneously more than one fluorescence signal, and allow a homogeneous illumination for obtaining different images from the object illuminated by comprising a spatial filter pattern () masking a defined filtering fraction of a first illumination path () on the filter and masking a defined filtering fraction of a second illumination path () on the filter, wherein the filtering fraction of the first and the second illumination paths () are different. The invention further relates to an illumination filter system () for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope () or endoscope, in particular a multispectral fluorescence microscope, comprising such illumination filter ().

Illumination filter for an illumination filter system of a surgical multispectral fluorescence microscope having a spatial filter pattern

A method and device for autofocusing in a microscope (), wherein two preferably spot-shaped, markers () are generated on an object, the spacing (d) of the markers representing an indication of the defocusing of a working plane () in the object from the focal plane () of the microscope (). A focus drive () displaces the working plane () into the focal plane () as a function of the marker spacing (d). In order to allow rapid and exact focusing to be performed, a detector () acquires an image of the markers () generated on the object, an evaluation unit () determines the spacing of the markers (), and a control unit () adjusts, as a function of the determined marker spacing (d), the speed of the focus drive () at which the working plane () is displaced into the focal plane ().

Autofocusing method and device for a microscope

The present invention relates to an illuminating device for an operating microscope including two observation beam paths for a first observer and two observation beam paths for a second observer. An illuminating system provides two parallel illuminating beam paths and a deflecting device, for deflecting the parallel illuminating beam paths onto an object that is to be observed. The deflecting device includes a first semitransparent deflector element which is associated with a first observation beam path of the first observer and a first observation beam path of the second observer, and a second semitransparent deflector element, which is associated with a second observation beam path of the first observer and a second observation beam path of the second observer. The first illuminating beam path acts exclusively on the first deflector element and the second illuminating beam path acts exclusively on the second deflector element.

Illuminating device for an operating microscope

An endoscopic video measurement system having a proximal operating part, an insertion part, and a replaceable head that can be inserted thereon, and where the operating part contains a connection for supplying electrical and optical power, optical transmission means for the lens illumination are provided in the insertion part for an electronic image sensor positioned in the distal end portion, and the replaceable head contains optical transmission means for the lens illumination and lens imaging, is characterized in that, in the insertion part, for transmitting a measurement beam a single-mode optical fiber is provided, with which an optical system positioned in the distal end part of the insertion part for producing a collimated sample beam bundle is associated.

Endoscopic video measuring system

A plug-in unit with integral cable connection to the operating part of an endoscope and plug connections for lamps, mechanical, and/or electronic modules is characterized in that a hollow tube extending to the distal end of the endoscope is inserted into the plug-in unit by the integral cable connection and the operating part and has its proximal end positioned so that it is freely movable in the plug-in unit in such a way that can be conducted out of a closeable bore-hole in the wall of the plug-in unit.

Connector unit for endoscopes

A surgical fluorescence stereomicroscope () for detecting and operating on fluorescing areas of an object field () is described, which microscope encompasses a first illumination device () for irradiating the object field () with light in an excitation wavelength region (E). The surgical fluorescence stereomicroscope () further encompasses an observation beam path () for guiding the reflected and emitted light received from the object field (), and a first observation filter () in the observation beam path () which is transparent in the excitation wavelength region (E) and in a fluorescence wavelength region (F). According to the present invention, means (to) for controllable attenuation in the excitation wavelength region (E) are additionally arranged in the observation beam path.

Surgical fluorescence stereomicroscope

The present invention relates to an afocal zoom system for a microscope with a shutter for controlling the depth of focus of the microscopic image produced by an object, wherein at least one shutter is disposed in front of the first lens group of the zoom system, viewed from the object, in the direction of the beam path passing through the zoom system, and/or at least one shutter is disposed on a lens group of the zoom system, the diameter of which can be varied in order to control the depth of focus, without causing vignetting of the edge beams.

Zoom system for a microscope and method of operating such a zoom system

An illumination device for a microscope has a variable working distance (d, d'), at which an object is illuminated obliquely from two different directions. Light from a light source is split into at least two illumination beam paths. In order to adapt to the different working distances, the light is subjected to an angle change before splitting or, if after splitting, then respectively by the same amount in both beam paths. A deviating element with at least two reflective surfaces is arranged in one of the illumination beam paths to induce a change in an angle at which one of the illumination beam paths strikes the object, in the same sense as another illumination beam path. The reflective surfaces may be arranged so that the illumination beam paths strike essentially the same region of the optical axis even with different working distances.

Illumination device for a microscope

The present invention relates to a stereo microscope () with a first and a second main beam path (), the spacing of which defines a stereo base (), wherein an axis of the microscope () extends through the middle of the stereo base () parallel to the main beam paths (), and with an optical beam splitter device () for producing an assistant beam path () and a documentation beam path (), wherein the direction of the assistant beam path () in a first position is rotated by 180&#xb0; to the direction of the assistant beam path () in a second position of the beam splitter device (), and the decoupled documentation beam path () in both positions of the beam splitter device () is in each case perpendicular to the decoupled assistant beam path (), and wherein in both the first and second positions of the beam splitter device () the assistant beam path () can in each case be decoupled at least from the first main beam path () and the documentation beam path () can in each case be decoupled at least from the second main beam path ().

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Widnau, Switzerland

Manfred Kuster