Aventis Pharma Deutschland, Gmbh

Hoechst Aktiengesellschaft

Medicis Pharmaceutical Corporation

Manfred Bohn

Karl Theodor Kraemer

Astrid Markus

Ulrich Stache

Hans-Georg Alpermann

Walter Dittmar

Eberhard Futterer

Heinz G Peil

Walter D&uuml;rckheimer

Walter D Urckheimer

Compounds of the formula (I) are disclosed and are suitable for the treatment of seborrheic dermatitis. 

Use of 1-hydroxy-2-pyridones for the treatment of seborrheic dermatitis

A pharmaceutical preparation comprising a hydrophilic gel-forming agent, water and a compound of the formula Iis suitable for the treatment and prophylaxis of dermatomycoses.

Antimycotic gel having high active compound release

Antimycotic gel with high active substance release

Corticoid 17,21-dicarboxylic esters and corticosteroid 17-carboxylic ester 21-carbonic esters, processes for their preparation and pharmaceuticals containing these compounds

The inventive powder preparations containing at least one compound of formula (I) are suited for treating leg ulcers or decubitus ulcers.

Utilization of powder preparations containing hydroxypyridones for treating leg ulcers and decubitus ulcers

Use of 1-hydroxy-2-pyridones for the treatment of skin diseases

Use of 1-hydroxy-2-pyridones for treating mucosa diseases which are difficult to treat

This invention relates to a nail polish comprising one or more glucocorticoids useful in treating nails which show changes due to the syndrome of psoriasis.

Antipsoriatic nail polish

Use of glyceryl triacetate for treating onychomycoses

Preparations stimulating nail growth

17-Deoxycorticoid-21-carboxylic esters of the formula I ##STR1## are described, in which A is CHOH and CHCl, CH.sub.2, C.dbd.O or 9(11) double bond; Y is H, F or Cl; Z is H, F or CH.sub.3 ; R(1) is aryl or hetaryl and R(2) is H or methyl. They are obtained by reacting a compound of the formula II, ##STR2## in which R(4) is OH, with an activated carboxylic acid of the formula III,

17-deoxycorticosteroid-21-�O!carboxylic esters, processes for their

Corticoid 17-alkyl carbonate 21-carboxylic and carbonic esters of the formula I ##STR1## are described in which A is CHOH and CHCl, CH.sub.2, C.dbd.O or 9(11) double bond; Y is H, F or Cl; Z is H, F or CH.sub.3 ; R(1) is aryl or hetaryl; n and m are zero or 1; R(2) is alkyl or --(CH.sub.2).sub.2 --OCH.sub.3 ; R(3) is H or methyl. They are obtained by reacting a compound of the formula II, ##STR2## in which R(5) is OH, with an activated carboxylic acid of the formula III,

Corticosteroid 17-alkyl carbonate 21-[0]-carboxylic and carbonic esters,

A nail lacquer containing at least one film-former which is insoluble in water and at least one substance which has antimycotic activity and is from the group comprising tioconazole, econazole, oxiconazole, miconazole, tolnaftate and naftifine hydrochloride.

Nail lacquer with antimycotic activity, and a process for the

A nail varnish comprising a water-insoluble film-forming substance and an antimycotic compound which is a 1-hydroxy-2-pyridone I of the general formula ##STR1## in which R.sup.1 is a hydrocarbon group which contains from 6 to 9 carbon atoms, but is free from olefinic and acetylenic bonds, one of the groups R.sup.2 and R.sup.4 is hydrogen and the other is hydrogen, methyl or ethyl and R.sup.3 is alkyl having up to two carbon atoms, said antimycotic ingredient being present in free form or in the form of a salt.

Growing community of inventors

Hofheim, Germany

Manfred Bohn