University of Arkansas

The Texas A&m University System

University of Guelph

Mandy Cox

Billy M Hargis

Luc Berghman

Sherryll Layton

Young Min Kwon

Walter G Bottje

Kimberly Cole

John R Barta

Guillermo Tellez

Saeed El-Ashram

Said El-Ashram

Walter Bottje

Vaccines comprising TRAP polypeptides andvectors comprising TRAP polypeptides are provided. The vaccines may also include a CD154 polypeptide capable of binding to CD40. Also provided are methods of enhancing an immune response against Apicomplexan parasites and methods of reducing morbidity associated with infection with Apicomplexan parasites.

Compositions and methods of enhancing immune responses to

Compositions and methods of enhancing immune responses to Eimeria

Provided herein are13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response against Influenza A and methods of reducing morbidity associated with an Influenza A infection. Methods of enhancing an immune response to a vaccine vector by expressing a polypeptide of CD154 capable of binding CD40 are also disclosed. Methods of developing a bacterial vaccine vector are disclosed. Methods of generating scarless site-specific mutations in a bacterium are also disclosed.

Compositions and methods of enhancing immune responses

Vaccines comprising fliC and CD 154 polypeptides andvaccine vectors comprising fliC polypeptides are provided. Also provided arc methods of enhancing an immune response against flagellated bacteria and methods of reducing morbidity associated with infection with flagellated bacteria.

Compositions and methods of enhancing immune responses to flagellated bacterium

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Provided herein are13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response against Influenza A and methods of reducing morbidity associated with an Influenza A infection. Methods of enhancing an immune response to a vaccine vector by expressing a polypeptide of CD 154 capable of binding CD40 are also disclosed. Methods of developing a bacterial vaccine vector are disclosed. Methods of generating scarless site-specific mutations in a bacterium are also disclosed.

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Fayetteville, AR, United States of America

Mandy Cox