Umm Al-qura University

Manal Mohamed Khowdiary

Nashwa Mostafa Saleh

Ammona Salem Mohamed

Moshera Zaki Mohamed

The present application discloses a method of synthesizing metal-based cationic surfactants and further their usage as anti-tumor and anti-bacterial agents. For the synthesis, selenius acid is mixed with sulfonamide to form sulfonammonium hydrogen selenites. Cobalt and Platinum hydrogen selenite dehydrate were then synthesized, and refluxed with sulfonammonium hydrogen selenites to form the disclosed Cobalt/Platinum ammonium hydrogen selenite complexes. Both complexes were mixed with cyclodextrin oligosaccharide to form nanoparticles, which were tested for anti-tumor/cancer and anti-bacterial effects.

Method of making metal based cationic surfactant nano particles and their use

A method of making benzidine hydrogen selenite complex with Cobalt and Platinum as surfactants is discussed. The resultant benzidine hydrogen selenite complex with either Cobalt or Platinum was characterized for its unique and superior properties. The complexes were characterized by elemental analysis, FTIR, and spectroscopy. The critical micelle concentration and thermodynamic parameters were calculated. The Values of IC50 were also calculated for the prepared complexes as well as their parent complex. The method of using the benzidine hydrogen selenite complex with cobalt and platinum as an antitumor agent to treat cancer is also demonstrated.

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Makkah, Saudi Arabia

Manal Mohamed Khowdiary