Celltrion Inc.

International Vaccine Institute

Postech Foundation

Daewoong Pharmaceutical Co., Ltd.

Genexine, Inc.

Dong-a Pharmaceutical Co., Ltd

Man Ki Song

Min Jung Kim

Young Chul Sung

Shin Jae Chang

Se Hwan Yang

Won Bae Kim

Sung Hee Lee

Seung Kew Yoon

Pan Kyeom Kim

Jung Sun Ahn

Soo Young Lee

Byung Pil Lim

Sang Tae Park

Eun Bee Park

Chang Geun Lee

Jae Ouk Kim

Sun Ju Keum

Jung Ah Choi

Chae Young Kim

Jong Moon Son

Byung Moon Kim

Se Jin Im

Su Hyung Park

This invention relates to an adjuvant composition containing at least one binding molecule for neutralizing influenza virus and a vaccine composition containing the same. The composition containing at least one binding molecule for neutralizing influenza virus is capable of increasing the effects of a vaccine, and can thus be used as an adjuvant, which increases an immune response upon vaccine administration, and is very useful in the prevention of diseases caused by viruses.

Adjuvant composition containing at least one influenza virus neutralizing and binding molecule and vaccine composition containing same

The present invention relates to astrain, of which the surface exposure of a protective antigen existing on a cellular membrane is increased due to the destruction of a wzy gene ofsp., and to a vaccine composition for treating or preventing shigellosis, containing the mutantstrain as an active ingredient. Thestrain of the present invention has a cell wall with a reduced thickness since a gene encoding a protein necessary for polymerization of the O-saccharide antigen is deleted, and as a result, membrane antigens including protein antigens commonly existing in differentspp. are more exposed to immune cells, and thus thestrain can be favorably used as a vaccine composition for treating or preventing shigellosis, derived from variousspp.

Vaccine composition for treating or preventing shigellosis

Growing community of inventors

Seoul, South Korea

Man Ki Song