Canon Kabushiki Kaisha

Mamoru Tsukada

Yasuyuki Tamura

Tomohiro Suzuki

Takayuki Yagi

Tatsuo Furukawa

Toshifumi Fukui

Hiroto Yoshii

Akira Asai

Nobuko Yamamoto

Mie Ishii

Masahiro Kawaguchi

Katsuhiko Shinjo

Hidenori Watanabe

Masaya Ogura

Yoshimasa Okamura

Provided is a probe set that is useful for identifying each allele of HLA individually, and a method of identification of an allele of HLA by the use thereof for each type. The probe set is composed of probes that cover all of the partial sequences that contain a unique base to each allele. Using this probe set HLA contained in a specimen is identified.

Probe set and method for identifying HLA allele

An infectious etiologic agent detection probe set which detects an infectious etiologic agent gene, includes a plurality of kinds of probes including oligonucleotide having base sequences selected from each of a plurality of groups selected from a first group including base sequences of SEQ ID Nos. 1 to 14 and complementary sequences thereof, a second group including base sequences of SEQ ID Nos. 15 to 24 and complementary sequences thereof, a third group including base sequences of SEQ ID Nos. 25 to 36 and complementary sequences thereof, a fourth group including base sequences of SEQ ID Nos. 37 to 47 and complementary sequences thereof, a fifth group including base sequences of SEQ ID Nos. 48 to 57 and complementary sequences thereof, a sixth group including base sequences of SEQ ID Nos. 58 to 68 and complementary sequences thereof, a seventh group including base sequences of SEQ ID Nos. 69 to 77 and complementary sequences thereof, an eighth group including base sequences of SEQ ID Nos. 78 to 85 and complementary sequences thereof, a ninth group including base sequences of SEQ ID Nos. 86 to 97 and complementary sequences thereof, and a 10th group including base sequences of SEQ ID Nos. 98 to 106 and complementary sequences thereof.

Infectious etiologic agent detection probe and probe set, carrier, and genetic screening method

To provide a method of accurately and efficiently acquiring a candidate for a set of discrimination elements for identification. Provided is a method of acquiring a set of specific elements on a specific sequence for discriminating the specific sequence from a number of sequences, including the steps of acquiring a group of alignment data in which each of the number of sequences is subjected to alignment processing, and acquiring a set of elements capable of discriminating the specific sequence through computational processing on the group of alignment data.

Method of acquiring a set of specific elements for discriminating sequence

The present invention provides a method for PCR amplification reaction that can reduce the time required for amplification reaction of nucleic acid by PCR using the target nucleotide molecule as a template, and an apparatus used for the method. The method comprises using a PCR reaction vessel in which a heater for local heating, which can thermally contact with a solution storing section with an extremely small capacity for storing a PCR reaction solution and a reaction solution stored in the solution storing section directly, is placed; feeding a pulsed current to the placed heater; and carrying out a thermal cycle of PCR reaction, so that high-speed PCR amplification reaction can be carried out.

PCR amplification reaction apparatus and method for PCR amplification reaction using apparatus

The analytical method having both flow cytometery and cytodiagnosis functions comprises the steps of: preparing a sample containing particulate substances such as cells and viruses; injecting the sample into a plate-like sample container; centrifuging the sample container; and using the sample container in which a distribution of the particulate substances has been formed as a preparation for analysis. The preparation is scanned with a laser beam to obtain analytical data. An analytical device for this method is also provided.

Analytical method and device using disc cytometry

In a driving method of an ink-jet recording head, heat is generated by applying a drive signal to a heating element, and this heat is applied to ink to generate a bubble and discharge the ink through a discharge outlet. The drive signal comprises a first drive signal for storing foaming energy in the ink, and a second drive signal for generating a bubble in the ink. The second drive signal has a signal time shorter than the boundary foaming time at which foaming energy decreases in a case of performing foaming only by the second drive signal. The first drive signal is applied prior to the second drive signal in order to compensate for a decrease in foaming energy.

Driving method of ink-jet recording head, and recording apparatus for performing the driving method

A fundus blood flow metering method includes a series of steps of carrying out alignment of the positional relation with an eye to be examined, carrying out aiming of a blood vessel to be measured, and measuring a velocity of blood flow while tracking the blood vessel so as to track and capture eye movement. After the sequential operation, the direction of incidence of a measuring beam is switched to another direction and the series of steps are again carried out for the same blood vessel, starting from the alignment.

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Fujisawa, Japan

Mamoru Tsukada