Imperial Chemical Industries Limited

Malcolm Johnson

Stuart D Mills

Paul J Phillips

The invention concerns the novel amine 1-(2-chlorobenzyl)-1,2,3,6-tetrahydropyridine of the formula: ##STR1## and its pharmaceutically acceptable acid-addition salts, which have useful properties in inhibiting the aggregation of blood platelets, and are of application in the treatment or propyhylaxis of thrombosis or occlusive vascular disease. The invention also provides pharmaceutical compositions of, and analogy processes for the manufacture of the amine of formula I, or a salt thereof.

Tetrahydropyridine derivative

The invention concerns the novel amine 1-(2-chlorobenzyl)-1,2,3,6-tetrahydropyridine of the formula: ##STR1## and its pharmaceutically acceptable acid-addition salts, which have useful properties in inhibiting the aggregation of blood platelets, and are of application in the treatment or prophylaxis of thrombosis or occlusive vascular disease. The invention also provides pharmaceutical compositions of, and analogy processes for the manufacture of the amine of formula I, or a salt thereof.

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Wilmslow, United Kingdom

Malcolm Johnson