Colgate Palmolive Company

Malathy Subramanian

Orum D Stringer

John C Brahms

Abdul Gaffar

John J Afflitto

Ernest E Kelly

Stuart Shapiro

Ernest Kelly

An oral antiplaque composition for treatment of teeth wherein the essential antiplaque agent is a substantially water insoluble noncationic antibacterial phenol containing, relative to the hydroxyl group, an alkyl or cycloalkyl group, preferably tert.-butyl (t-butyl), in the 2-position, and substituents in one or both of the 4- and 5-positions, one or both of which may be alkyl or cycloalkyl, one being preferably t-butyl.

Antiplaque oral composition and method

An antiplaque composition comprising a bacteriocin such as nisin and a polyphosphonate.

Oral composition

An oral antiplaque composition and treatment of teeth therewith wherein the essential antiplaque agent is a substantially water insoluble noncationic antibacterial phenol containing, relative to the hydroxyl group, an alkyl or cycloalkyl group, preferably tert.-butyl (t-butyl), in 2-position, and substituents in one or both of the 4- and 5-positions, one of which may be phenyl or 2', 3' and/or 4' substituted alkyl or cycloalkyl phenyl, preferably 4'-t-butyl phenyl or a phenanthrene containing a hydroxyl substituent in the 2- or 3-position and alkyl or cycloalkyl, preferably t-butyl, substituents in the other of the 2- and 3-positions and in at least one of the other rings. Novel antibacterial alkylated phenols are also described.

Mouthrinses containing sanguinaria of improved anti microbial efficacy and stability are attained by including in the mouthrinse a surfactant combination of an amidobetaine and poly(oxyethylene)-poly(oxypropylene) block copolymer.

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Somerset, NJ, United States of America

Malathy Subramanian