Nihon Medi-physics Company, Limited

Makoto Kato

Masaaki Hazue

Nobuo Ueda

Hiroaki Matsushima

A non-radioactive composition for intracorporeal labeling of red blood cells with radioactive technetium, which comprises as the essential components (a) at least one of pyridoxal and its salts, (b) at least one stannous salt and (c) at least one .alpha.-amino acid of which the administeration through a vein in a living body can assure an efficient intracorporeal labeling of red blood cells in the living body with radioactive technetium which is subsequently administered through the vein.

Composition for labeling of red blood cells with radioactive technetium

A method for production of a thallium-carrying target material comprising a thermo-conductive support and metallic thallium electro-plated thereon, which comprises applying a DC-AC overlapped electric current between an anode made of a metal or its alloy having a lower ionization tendency than hydrogen and the electro-conductive support as a cathode, both electrodes being immersed in a bath of an electro-plating solution comprising monovalent thallium ions in the presence of at least one of aromatic amines and phenols, so as to deposit the thallium metal on the surface of the thermo-conductive support.

Thallium-carrying target material and its production

A .sup.99m Tc-labeled radioactive diagnostic agent, prepared by contacting .sup.99m Tc in the form of a pertechnetate with a non-radioactive carrier comprising pyridoxal or salt thereof, a stannous salt and an .alpha.-amino acid not having any hydrophilic functional group dissolved in an aqueous medium. This diagnostic agent is suitable for the examination of hepatobiliary ducts due to its smooth transfer through the hepatobiliary ducts as well as its high stability and non-toxicity.

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Kobe, Japan

Makoto Kato