Shionogi Company Limited

Daikin Industries, Ltd.

Makoto Adachi

Masahiro Fuji

Tsutomu Sugasawa

Susumu Takada

Mitsuaki Ohtani

Akira Matsushita

Kazuyuki Sasakura

Takashi Sasatani

Nobuo Chomei

Tomoyuki Ogawa

Tetsuo Okada

Masami Eigyo

Yoshikazu Fukui

Moriyasu Masui

Naoki Tsuno

Hiromu Matsumura

Hidenori Mikamiyama

Akira Matsumura

Tatsuo Toyoda

Yuuichi Yamamoto

Yuusuke Fujii

Kazuo Kawasaki

Keita Honda

A rotary compressor includes a compression mechanism, a casing, a motor stator and a motor rotor. The motor stator includes stacked steel plates, teeth, and slots. The stacked steel plates are fixed to an inner surface of the casing. A number of the teeth and slots is nine. The motor rotor rotates a crankshaft to drive the compression mechanism. The stacked steel plates have first to ninth areas radially outside the nine teeth, first concave portions provided in five of the areas, and a second concave portion provided in at least one of four areas other than the five areas. The five first concave portions and an inner circumferential surface of a cylindrical portion form five first passages. The second concave portion and the inner circumferential surface of the cylindrical portion form at least one second passage.

Rotary compressor

A compressor includes a compression mechanism, a casing, and a temperature detector. The compression mechanism includes a rotation axis. The casing accommodates the compression mechanism. The casing includes a compression mechanism contact portion. The compression mechanism is in contact with an inner surface of the compression mechanism contact portion. The temperature detector is attached to an outer surface of the compression mechanism contact portion and is configured to sense temperature of the compression mechanism contact portion.

Compressor having casing and temperature detector thereon

It was found out that the nitrogen-containing heterocyclic derivative represented by the formula (I) specifically binds to a receptor of NR1/NR2B, and is used as a NR2B receptor antagonist. A compound represented by: wherein Z is N or CR, Ais a nitrogen-containing aromatic monocyclic group which is optionally substituted, a nitrogen-containing aromatic fused cyclic group which is optionally substituted etc., Ais an aromatic hydrocarbon cyclic group or an aromatic heterocyclic group, each optionally having a substituent, R, R, R, R, Rand Rare each independently hydrogen, hydroxy, etc., w is 2 or 3, t is 1 or 2, X is &#x2014;(CRR)m-, &#x2014;CO(CRR)n-, &#x2014;CONR(CRR)n- etc., m is an integer of 1 to 4, n is an integer of 0 to 4, Rand Rare each independently hydrogen, halogen, hydroxy etc., and Ris hydrogen or lower alkyl,or a pharmaceutically acceptable salt, or a solvate thereof.

Nitrogen-containing heterocycle derivatives substituted with cyclic group

Having an affinity against serotonine receptors, compound (I) shown below is useful as a therapeutic agent against various kinds of diseases of central nervous systems;(wherein Ris hydrogen; Ris hydrogen or lower alkyl; Ris hydrogen, &#x2014;COORand so on; Ris hydrogen, lower alkyl and so on, or Rand Rtaken together may form &#x2550;O or &#x2550;S; Ris hydrogen, or Rand Rtaken together may form a bond; Ris hydrogen, &#x2014;COORand so on; Ris hydrogen, halogen, lower alkyl and so on; Ris hydrogen, lower alkyl, cycloalkyl and so on; R, Rand Rare each independently hydrogen, halogen, lower alkyl and so on).

Tricyclic indole compounds having affinity for serotonin receptor

Tricyclic azaindolizine derivatives having an sPLA2-inhibitory activities

Tricyclic compounds having sPLA2-inhibitory activities

Pyrrolo&lsqb;1,2-b&rsqb; pyridazine derivatives having sPLA2 inhibitory effect

An oxopyridinylquinoxaline derivative represented by the following Formula I or pharmaceutically acceptable salts thereof: ##STR1## wherein R.sup.1 is hydrogen, halogen, nitro, or trihalomethyl; R.sup.2 is hydrogen, halogen, nitro, cyano, trihalomethyl, carbamoyl, carbamoyl substituted with lower alkyl, sulfamoyl, or sulfamoyl substituted with lower alkyl; R.sup.3 is hydrogen, nitro, or halogen; R.sup.4 is hydrogen, lower alkyl, substituted lower alkyl, lower cycloalkyl, or substituted lower cycloalkyl; R.sup.5 's are substituents independently selected from the group consisting of halogen, nitro, cyano, lower alkyl, carbamoyl, and carbamoyl substituted with lower alkyl; and n is an integer of 0 to 4. The derivative works as an antagonistic agent against both the NMDA receptors and the AMPA receptors, so that it is effective as a therapeutic agent for neurological disorders caused by excitatory amino acids binding to the receptors.

Oxopyridinylquinoxaline derivative

A compound of the formula: ##STR1## wherein R is an optionally substituted phenyl group, 5-membered; the A ring is a 5 to 7 membered alicyclic group in which said A ring may have an alkyl group as a substituent, or a pharmaceutically acceptable salt thereof, and is useful as a psychotropic agent.

Condensed imidazopyridine derivatives

A compound of the formula: ##STR1## wherein R is an optionally substituted aryl group or an optionally substituted aromatic heterocycle group; A ring is a 5 to 9 membered alicyclic group, in which one or more of carbon atoms constituting said A ring may be replaced by O, or S and said A ring may have alkyl as a substituent, or a pharmaceutically acceptable salt thereof.

The present invention relates to preparation of imidazoles which are useful as pharmaceutical and agricultural chemicals. Specifically, the present invention relates to a process for preparing imidazoles of the formula (I): ##STR1## which comprises conducting condensation among an .alpha.,.alpha.-dihaloaldehyde compound of the formula (II): ##STR2## an aldehyde compound of the formula: R.sup.2 --CHO and aqueous ammonia.

Preparation of imidazoles

A process for ortho-cyanation of phenols or phenylamines which comprises reacting a phenyl compound having hydroxy or optionally substituted amino or cyclic amino, of which ortho position is vacant, with trichloroacetonitrile, C.sub.1 -C.sub.5 alkyl thiocyanate or C.sub.6 -C.sub.12 aryl thiocyanate in the presence of a boron trihalide and treating the resultant product with an alkali is provided, and said process is useful in the synthesis of intermediates for medicinals or pesticides.

Process for ortho-cyanation of phenols or phenylamines

Improvement in the production of psychotropic 1-substituted-1,3-dihydro-1,4-benzodiazepin-2-ones starting from 2-(1-substituted)amino-benzophenonimines through novel intermediates of the formula: ##STR1## (wherein R is hydrogen, methyl or benzyl, R.sup.1 is C.sub.1 -C.sub.5 alkyl or phenyl-C.sub.1 -C.sub.5 alkyl, X and Y each is hydrogen or halogen and n is an integer of 1 to 2) with economical and industrial advantage.

Process for preparing 1-substituted-1,4-benzodiazepine derivatives

1,4-Benzodiazepine derivatives of the formula: ##STR1## (in which R.sup.1 is pyrrolidinyl or piperidinyl each optionally substituted by C.sub.1-3 alkyl, phenyl-C.sub.1-3 alkyl, C.sub.1-5 alkanoyl, or C.sub.2-5 alkoxycarbonyl,

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Osaka, Japan

Makoto Adachi