Mitsubishi Chemical Industries Limited

Mitsubishi Kasei Corporation

Nippon Shinyaku Company, Ltd.

Nec Corporation

Makio Kobayashi

Hiromi Okushima

Akihiro Narimatsu

Yoshimi Kitada

Hiroshi Enomoto

Rikizo Furuya

Kazuo Wagatsuma

Hiroaki Munakata

Makoto Tsurufuji

Shigeru Sato

Akihiro Tobe

Makoto Sugiyama

Iwao Morita

Yoshihisa Shibata

Tetsuro Shimpuku

Shingo Matsumura, Deceased

Junko Hayashi

Asami Seino

Miyuki Morita

Hideki Bessho

Isao Shimooda

Naoya Satoh

A flat keyboard switch comprises a printed circuit board having a plurality of fixed contacts and a light emitting element provided thereon, a diaphragm disposed above the fixed contacts and serving as a movable contact for electrically connecting the fixed contacts to each other, a surface sheet having an indicium printed at a portion thereof above the diaphragm, the indicium being made of a material having a light transmitting property, a movable element disposed between the diaphragm and the surface sheet, a light introducing plate disposed in the neighborhood of the light emitting element for scattering light emitted from the light emitting element toward the movable element, and a light introducing member interposed between the movable element and the light introducing plate being formed as a unitary member together with the movable element and the light introducing plate.

Flat keyboard switch

Disclosed are antihypertensive pharmaceutical compositions and compounds which include the thiocarbamoylacetonitrile having the formula: ##STR1## wherein: R.sup.1 is selected from the group consisting of hydrogen, a C.sub.1 to C.sub.6 alkyl, a C.sub.3 to C.sub.6 cycloalkyl or --(CH.sub.2).sub.n --A (where A is selected from the group consisting of a C.sub.6 to C.sub.12 aryl, a 5- or 6-membered heterocyclic group or a fused heterocyclic group constituted by 9 or 10 atoms, each of which may be substituted by at least one substitute group selected from a C.sub.1 to C.sub.6 alkyl and a halogen and n is 0 or an integer of 1 to 6),

Antihypertensive thiocarbamoylascetonitrile compounds

There is disclosed an aminobenzenesulfonic acid derivative of the formula: ##STR1## wherein R.sub.1 represents hydrogen atom, a C.sub.1 -C.sub.6 alkyl group, a C.sub.3 -C.sub.7 cycloalkyl group, a C.sub.1 -C.sub.4 halogenated alkyl group, a halogen atom or a C.sub.6 -C.sub.12 aryl group, R.sub.2 represents hydrogen atom, a C.sub.1 -C.sub.6 alkyl group or a C.sub.7 -C.sub.12 aralkyl group which may have at least one substituent selected from cyano group, nitro group, C.sub.1 -C.sub.6 alkoxy groups, halogen atoms, C.sub.1 -C.sub.6 alkyl groups and amino groups, and n represents an integer of 1 to 4, of a pharmaceutically acceptable salt thereof.

Aminobenzenesulfonic acid derivatives

There are provided novel pyridazinone derivatives having the general formula (I): ##STR1## wherein A represents 5- or 6-membered heterocyclic ring having 1-3 nitrogen atoms, which may be substituted by at least one member selected from the group consisting of C.sub.1-5 alkyl, cyano, hydroxyl, C.sub.1-5 alkoxyl, amino, C.sub.1-5 alkylamino, C.sub.2-6 dialkylamino, C.sub.2-5 acylamino, carboxyl, C.sub.2-5 alkoxycarbonyl and carbamoyl, and R.sup.1 and R.sup.2 independently represent hydrogen atom or C.sub.1-5 alkyl or R.sup.1 and R.sup.2 may form together C.sub.1-5 alkylene, and salts thereof.

Pyridazinone derivatives and salts thereof

Piperazinyl carbonyl phenyl pyridazinone derivatives useful as

Phenylacetic acid derivatives of the formula: ##STR1## wherein R.sup.1 is hydrogen or ##STR2## wherein R.sup.5 is an alkyl group of 1-6 carbon atoms or an aryl group; R.sup.2 and R.sup.3 are independently hydrogen or an alkyl group of 1-4 carbon atoms; R.sup.4 is hydrogen or an alkyl group of 1-4 carbon atoms, have been found to possess immunomodulating activity.

Immunomodulating agent

There are provided novel pyridazinone derivatives having the general formula (I): ##STR1## wherein A represents 5- or 6-membered heterocyclic ring having 1-3 nitrogen atoms, which may be substituted by at least one member selected from the group consisting of C.sub.1-5 alkyl, cyano, hydroxyl, C.sub.1-5 alkoxy, amino, C.sub.1-5 alkylamino, C.sub.2-6 dialkylamino, C.sub.2-5 acylamino, carboxyl, C.sub.2-5 alkoxycarbonyl and carbamoyl, and R.sup.1 and R.sup.2 independently represent hydrogen atom or C.sub.1-5 alkyl or R.sup.1 and R.sup.2 may form together C.sub.1-5 alkylene, and salts thereof.

Pyridazinone derivatives and salts thereof as cardiac stimulants

Glutamine derivatives and non-toxic salts thereof have been found to have immunomodulating activities.

Glutamine derivatives

Growing community of inventors

Machida, Japan

Makio Kobayashi