Wisconsin Alumni Research Foundation

Majed M Hamawy

Stuart J Knechtle

Disclosed herein are methods for monitoring the immunological status of transplant recipients. Fibroblast cells derived from transplanted organs are used in proliferation assays with lymphocytes taken from the recipient after transplantation. The comparison of assay results in the presence of, and in the absence of (or in the presence of reduced levels of) a cytokine growth factor such as interleukin-2, is used to determine whether the organ is being rejected. Also disclosed are kits for practicing these methods.

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Madison, WI, United States of America

Majed M Hamawy