Kyowa Hakko Kogyo Co., Ltd.

Kyowa Hakko Kirin Co., Limited

Maiko Hirota

Kazuyasu Nakamura

Kenya Shitara

Naoki Shimada

Nobuo Hanai

Motoo Yamasaki

Akiko Furuya

Akira Tanaka

The present invention relates to an antibody against FGF-8, particularly a humanized antibody against FGF-8 and the antibody fragment thereof, a DNA sequence encoding the above antibody or the antibody fragment, a vector comprising the DNA sequence and a host cell transformed by the vector, a production process of the above antibody or the antibody fragment using the host cell, and a therapeutic agent and a diagnostic agent for cancer using the antibody or the antibody fragment.

Humanized antibody against fibroblast growth factor-8 and antibody fragment thereof

A method for preventing or treating a disease, comprising administering to human or animal in need of such prevention or treatment an effective amount of a monoclonal antibody which specifically binds to FGF-8 and inhibits FGF-8 activity.

Anti-fibroblast growth factor-8 monoclonal antibody

Growing community of inventors

Tokyo, Japan

Maiko Hirota