Taisho Pharmaceutical Co., Ltd.

Toyama Chemical Co., Ltd.

Mai Yokotani

Tadashi Tanaka

Taro Kiyoto

Hiroki Urabe

Fumihito Ushiyama

Yasuhiro Tsutsui

Toshiya Noguchi

Junichi Ando

Hiromasa Horikiri

Disclosed is a compound represented by the general formula: wherein Rrepresents an aryl or heterocyclic group which may be substituted or the like; Xrepresents a C-Calkylene group or the like; X, Xand Xindependently represent NH, a bond or the like; Xrepresents a lower alkylene group, a bond or the like; Yrepresents a bivalent alicyclic hydrocarbon residue which may be substituted or a bivalent alicyclic amine residue which may be substituted; and Z, Z, Z, Z, Zand Zindependently represent a nitrogen atom, a group represented by the formula: CH, or the like, provided that at least one of Z, Z, Zand Zrepresents a nitrogen atom, or a salt thereof, which is useful as an antibacterial agent.

Heterocyclic compound or salt thereof and intermediate thereof

Disclosed is a compound represented by the general formula: [wherein Rrepresents an aryl or heterocyclic group which may be substituted or the like; Xrepresents a C-Calkylene group or the like; X, Xand Xindependently represent NH, a bond or the like; Xrepresents a lower alkylene group, a bond or the like; Yrepresents a bivalent alicyclic hydrocarbon residue which may be substituted or a bivalent alicyclic amine residue which may be substituted; and Z, Z, Z, Z, Zand Zindependently represent a nitrogen atom, a group represented by the formula: CH, or the like, provided that at least one of Z, Z, Zand Zrepresents a nitrogen atom] or a salt thereof, which is useful as an antibacterial agent.

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Toyama, Japan

Mai Yokotani