King Saud University

Mai Abdelrahman Elobeid Wagealla

Manal Ahmed Gasmelseed Awad

Promy Virk

Awatif Ahmed Hendi

Khalid Mustafa Osman Ortashi

Rabia Qindeel

Atheer Mohammed Asiri

Sarah Saleh Abdulla Alsaif

Nouf Abdullah Mureet Al-Ghamdi

Nouf Abdallah Mureet Al-Ghamdi

Lulwah Saleh Mohammed Al Hassan

Amnah El-Enazy

Lulwah Saleh Mohammed Al-Hassan

Encapsulated resveratrol (RSV) nanoparticles having a resveratrol core, a gum arabic shell, and a polyvinyl alcohol coating over the gum arabic shell. In an embodiment, an RSV:gum arabic:polyvinyl alcohol (PVA) ratio in the encapsulated nanoparticles is about 1:5:5 (w/w/w). The encapsulated RSV nanoparticles can have an average size ranging from about 195 nm to about 210 nm.

Encapsulated resveratrol (RSV) nanoparticles

Thenanoparticles may be synthesized by harvestingleaves, drying theleaves, powdering the driedleaves, suspending the powderedleaves in a solution, and spraying the solution into boiling water under ultrasonic conditions to obtainnanoparticles. Thenanoparticles may be encapsulated by dissolving thenanoparticles and gum olibanum in ethanol to produce a mixture, injecting the inert organic phase of the mixture into an aqueous solution containing PVA, and homogenizing the aqueous solution. Thenanoparticles may be useful in preventing the growth of cancer cells and in treating diabetes by inhibiting &#x3b1;-glucosidase and/or &#x3b1;-amylase activity.

nanoparticles

A method of preparing probiotic nanoparticles can include dissolving formulated probiotics in methanol, spraying the methanol solution into boiling water under ultrasonic conditions to provide a sonicated solution, and stirring the sonicated solution to obtain probiotic nanoparticles. The probiotic nanoparticles may be cluster or rod-shaped. The probiotic nanoparticles may be administered to a subject to reduce oxidative stress or to treat diseases associated with oxidative stress.

Synthesis of probiotic nanoparticles

The method of treating diabetic wounds using biosynthesized nanoparticles includes administering an effective amount of silver and gold nanoparticles to a patient in need thereof. The silver and gold nanocomposite is prepared by 'biosynthesis', i.e., by providing a first aqueous solution of a noble metal salt or a noble metal oxide; providing a second solution of an aqueous plant extract, and combining the first solution and the second solution to produce a solution including nanoparticles of the noble metal. The second solution includes a plant extract obtained from-and. The metal salt can include silver nitrate (AgNO) and chloroauric acid (HAuCl). Nanoparticles of gold and nanoparticles of silver are prepared separately, and then mixed to obtain a composition containing a gold and silver nanocomposite.

Method of treating diabetic wounds using biosynthesized nanoparticles

A method of preparing hesperetin nanoparticles includes dissolving hesperetin in an organic solvent to form a solution; spraying the solution in boiling water while applying ultrasonic energy to form a mixture; and stirring the mixture for at least about 15 minutes at a speed of about 200-800 rpm to obtain the hesperetin nanoparticles.

Synthesis of hesperetin nanoparticles

A method of preparing naringenin nanoparticles comprises dissolving naringenin in an organic solvent to form a solution; adding the solution to boiling water under ultrasonic conditions to form a mixture; and stirring the mixture to obtain the naringenin nanoparticles. The organic solvent can be at least one of methanol, ethanol, dichloromethane and chloroform. Ultrasonic conditions can include applying ultrasonic energy at a frequency of 30-60 kHz and a power of 100 watts for about 20-30 minutes to the mixture.

Synthesis of naringenin nanoparticles

A method of preparing rosemary nanoparticles includes providing a solution including rosemary extract, spraying the rosemary extract solution into boiling water under ultrasonic conditions to produce a sonicated mixture, and freeze-drying the sonicated mixture to produce rosemary nanoparticles. The rosemary nanoparticles and encapsulated rosemary nanoparticles with polymers can have a particle size of about 69 nm to about 99 nm. The rosemary nanoparticles and encapsulated rosemary nanoparticles with polymers can be prepared without the use of metals.

Method of preparing rosemary nanoparticles and encapsulated rosemary nanoparticles

The synthesis of nanoparticles of metals and metal oxides using plant seeds extract involves providing a solution comprising a metal ion; providing a plant seeds extract solution that comprises a reducing agent; and combining the metal ion solution and the plant extract solution while stirring at room temperature to produce metal nanoparticles. The plant extract is obtained from-seeds, and the metal ion is selected from the group consisting of silver (Ag), gold (Au) and zinc (Zn).

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Riyadh, Saudi Arabia

Mai Abdelrahman Elobeid Wagealla