Sk Chemicals Co., Ltd.

Tiumbio Co., Ltd.

Sk Bioscience Co., Ltd.

Mahn-Hoon Park

Hun Rae Kim

Jin-Hwan Shin

Su-Jin Park

Myeong-Ju Noh

Ji-Hye Yang

Seon-Young Yang

Ji-Hye Lee

Bong-Yong Lee

Hun-Taek Kim

Hun Sung Kim

In-Young Song

Yun Jung Lim

Min-Sun Kim

Seo Yeon Son

Dong-Soo Ham

Ho-Soon Lee

A fusion protein comprising factor VII (FVII) and transferrin according to the present invention has an improved specific activity of FVII compared to existing FVII fusion proteins comprising other fusion partners than transferrin, and thus can be effectively used in a therapy using FVII.

Fusion protein having factor VII activity

Provided is an immunogenic composition comprising 15 different polysaccharide-protein conjugates. Each of the conjugates comprises a capsular polysaccharide prepared from different serotypeconjugated to a carrier protein, that is, serotypes 1, 2, 3, 4, 5, 6A, 6B, 7F, 9N, 9V, 14, 18C, 19A, 19F and 23F. An immunogenic composition formulated into a vaccine comprising an aluminum-based adjuvant increases application range with respect to pneumococcal diseases in infants and children.

Polyvalent pneumococcal polysaccharide-protein conjugate composition

Provided is an immunogenic composition comprising 13 different polysaccharide-protein conjugates. Each of the conjugates comprises a capsular polysaccharide prepared from a different serotypeconjugated to a carrier protein, that is, 12 serotypes selected from the group consisting of 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F and serotype 2 or 9N. The immunogenic composition formulated into a vaccine comprising an aluminum-based adjuvant increases coverage with respect to pneumococcal diseases in infants and children.

Multivalent pneumococcal polysaccharide-protein conjugate composition

The present invention provides an improved method of producing a capsular polysaccharide having a pneumococcal serotype. The method according to the present invention includes a step of additionally culturing bacterial cells producing a pneumococcal serotype without pH adjustment, thereby removing a protein precipitation process by acidification with a pH adjuster.

Production method for capsular polysaccharide having pneumococcal serotype

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Yongin-si, South Korea

Mahn-Hoon Park