Celgene Corporation

Mahan Abbasian

Jeonghoon Sun

Kandasamy Hariharan

Henry Chan

Heather K Raymon

David Mikolon

Gustavo Fenalti

Monica Wai Ling Leung

Konstantinos Mavrommatis

Carlo Steven Santos

Christina Valerie Trout

Laure Escoubet

Andrew Wurmser

Provided herein are compositions, methods and uses involving antibodies that specifically bind to signal regulatory protein-α (SIRPα) and modulate the activity of SIRPα.

SIRP-α binding proteins and methods of use thereof

Provided herein are compositions, methods and uses involving antibodies that specifically bind to signal regulatory protein-&#x3b1; (SIRP&#x3b1;) and modulate the activity of SIRP&#x3b1;.

SIRP-&#x3b1; binding proteins and methods of use thereof

Antibody species that bind B-Cell Maturation Antigen (BCMA) are provided as well as methods of depleting BCMA-expressing cells in a patient in need thereof, comprising administering a therapeutically effective amount of the antibody species or an entity comprising a BCMA binding fragment thereof. Methods of treating B cell-related disorders associated with BCMA expression in a patient in need thereof are provided, comprising administering to the patient a therapeutically effective amount of the antibody species or an entity comprising a BCMA binding fragment thereof.

BCMA-binding antibodies and uses thereof

Growing community of inventors

San Diego, CA, United States of America

Mahan Abbasian